Microenvironment (biology)

Microenvironment in biology is defined as the normal cells, molecules, and blood vessels that surround and feed a particular cellular area. The microenvironment in a tumor is different from that of a healthy organ; the microenvironment can affect how the tumor grows and spreads.[1] The term originated in the oncology literature in 1975[2] and has been used with increasing frequency in the biomedical literature since the 2000´s.[3]

References

  1. ↑ Microenvironment NCI Dictionary, undated, retrieved 7 December 2017
  2. ↑ Preisler HD, Bjornsson S, Mori M, Barcos M.Granulocyte differentiation by Friend leukemia cells.Cell Differ. 1975 Dec;4(5):273-83.
  3. ↑ Pubmed search on tumor microenvironment retrieved 7 December 2017


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