Michel Kahaleh

Dr. Kahaleh overseeing an Endoscopy during a live course workshop in 2017

Michel Kahaleh, MD, AGAF, FACG, FASGE is an American gastroenterologist and an expert in therapeutic and diagnostic endoscopy, including endoscopic retrograde cholangiopancreatography (ERCP), therapeutic endoscopic ultrasound (EUS) and other minimally invasive endoscopic procedures.[1]

He is the Founder and Director of both the Therapeutic Endoscopic Ultrasound Society[2] and Endoscopy Research Society.[3]

He is a Professor of Medicine, and is currently the Clinical Director of Gastroenterology, Chief of Endoscopy, and Director of the Pancreas Program at the Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey.[4]

Medical and research career

Trained in Erasme Hospital, University of Brussels by Michel Cremer and Jacques Deviere, he became the leader of the Pancreatico-Biliary group at the University of Virginia before joining Weill Cornell Medical College as the Chief of Endoscopy and Pancreas Program Director in July 2011.  Dr. Kahaleh's research is focused on interventional endoscopy, and the use of new devices to diagnose and treat various gastrointestinal disorders.

Dr. Kahaleh has conducted 30 clinical research studies[5] since 15 years and published 320 papers[6] and 200 national and international scientific presentations.[7]

Dr. Kahaleh doing Per-oral endoscopic myotomy with Dr. Haruhiro inoue

Dr. Kahaleh has been involved in in-vivo projects aiming at improving minimally invasive procedures such as per-oral endoscopic myotomy (POEM)[8][9] for achalasia,[10] gallbladder drainage,[11][11] biliary[12][12] and pancreatic[13][14] decompression. He is credited with creating a new endoscopic approach for biliary obstructions in altered anatomy patients called EUS-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE).[15][16][17]

He helped develop and validate new diagnostic criteria for improving accuracy in diagnosis of bile duct cancer using confocal laser endomicroscopy[18][19][20][21] called the Paris classification.[22][23] He led a team of expert endoscopists to develop and validate the Monaco classification[24] diagnostic criteria for bile duct cancer using the SpyGlass® Direct Visualization System for cholangioscopy.

Dr. Kahaleh was one of the first to publish on radio frequency ablation (RFA) for bile duct cancer and pancreatic cancer therapy using Dr. Nagy Habib's probe in the United States. He was the first to publish a clinical trial on photodynamic therapy (PDT) in the United States for bile duct cancer.[25][26] He was the first to conduct a pre-clinical study of a radio frequency ablation probe using endoscopic ultrasound (EUS-RFA) meant for treating pancreatic cancer.[27] The EUS-RFA probe was created by Dr. Nagy Habib and has been successfully used in humans after the pre-clinical study.[28]

Dr. Kahaleh has further published papers on additional minimally invasive endoscopic treatment for several conditions including pancreatic fluid collections,[29] gastroparesis,[30] gastric outlet obstruction,[31] obesity weight loss procedures,[32] esophageal tumors[33][34] and others.

Dr. Kahaleh has created a personalized training program which allowed him to train physicians on endoscopic submucosal dissection (ESD) and POEM in the USA, Italy, Spain, Colombia, Nicaragua, Ecuador, Mexico and Argentina.[35]

As the Founder of the Therapeutic Endoscopic Ultrasound Society,[36] along with colleague co-founder Dr. Todd Baron, Dr. Kahaleh has hosted the annual consortium on Therapeutic EUS during the Digestive Disease Week for the past 8 years.[37]

Honors and awards

References

  1. ↑ "Publications by Michel Kahaleh".
  2. ↑ "TEUSSOCIETY".
  3. ↑ "Endoscopy Research Society".
  4. ↑ "Rutgers Gastroenterology".
  5. ↑ "Clinical Trials Gov Listing of active studies".
  6. ↑ "Listing of Publications".
  7. ↑ "Michel Kahaleh biography".
  8. ↑ Kumta, Nikhil A.; Mehta, Shivani; Kedia, Prashant; Weaver, Kristen; Sharaiha, Reem Z.; Fukami, Norio; Minami, Hitomi; Casas, Fernando; Gaidhane, Monica (2014-9). "Peroral endoscopic myotomy: establishing a new program". Clinical Endoscopy. 47 (5): 389–397. doi:10.5946/ce.2014.47.5.389. ISSN 2234-2400. PMC 4198553. PMID 25324996. Check date values in: |date= (help)
  9. ↑ Tyberg, Amy; Sharaiha, Reem Z.; Familiari, Pietro; Costamagna, Guido; Casas, Fernando; Kumta, Nikhil A.; Barret, Maximilien; Desai, Amit P.; Schnoll-Sussman, Felice (2018-1). "Peroral endoscopic myotomy as salvation technique post-Heller: International experience". Digestive Endoscopy. 30 (1): 52–56. doi:10.1111/den.12918. ISSN 1443-1661. PMID 28691186. Check date values in: |date= (help)
  10. ↑ "Poem for Achalasia video".
  11. 1 2 Tyberg, Amy; Saumoy, Monica; Sequeiros, Enrique V.; Giovannini, Marc; Artifon, Everson; Teoh, Anthony; Nieto, Jose; Desai, Amit P.; Kumta, Nikhil A. (2018-1). "EUS-guided Versus Percutaneous Gallbladder Drainage: Isn't It Time to Convert?". Journal of Clinical Gastroenterology. 52 (1): 79–84. doi:10.1097/MCG.0000000000000786. ISSN 1539-2031. PMID 28009687. Check date values in: |date= (help)
  12. 1 2 Sharaiha, Reem Z.; Khan, Muhammad Ali; Kamal, Faisal; Tyberg, Amy; Tombazzi, Claudio R.; Ali, Bilal; Tombazzi, Claudio; Kahaleh, Michel (2017-5). "Efficacy and safety of EUS-guided biliary drainage in comparison with percutaneous biliary drainage when ERCP fails: a systematic review and meta-analysis". Gastrointestinal Endoscopy. 85 (5): 904–914. doi:10.1016/j.gie.2016.12.023. ISSN 1097-6779. PMID 28063840. Check date values in: |date= (help)
  13. ↑ Doshi, Rushabh; Rizk, Nada; Tyberg, Amy; Sharaiha, Reem Z.; Kahaleh, Michel (2016-7). "EUS-guided pancreatic drainage for recurrent pancreatitis". Gastrointestinal Endoscopy. 84 (1): 186–187. doi:10.1016/j.gie.2016.01.033. ISSN 1097-6779. PMID 26802203. Check date values in: |date= (help)
  14. ↑ Tyberg, Amy; Sharaiha, Reem Z.; Kedia, Prashant; Kumta, Nikhil; Gaidhane, Monica; Artifon, Everson; Giovannini, Marc; Kahaleh, Michel (2017-1). "EUS-guided pancreatic drainage for pancreatic strictures after failed ERCP: a multicenter international collaborative study". Gastrointestinal Endoscopy. 85 (1): 164–169. doi:10.1016/j.gie.2016.07.030. ISSN 1097-6779. PMID 27460387. Check date values in: |date= (help)
  15. ↑ "Bariatric News".
  16. ↑ Kedia, Prashant; Kumta, Nikhil A.; Widmer, Jessica; Sundararajan, Subha; Cerefice, Mark; Gaidhane, Monica; Sharaiha, Reem; Kahaleh, Michel (2015-2). "Endoscopic ultrasound-directed transgastric ERCP (EDGE) for Roux-en-Y anatomy: a novel technique". Endoscopy. 47 (2): 159–163. doi:10.1055/s-0034-1390771. ISSN 1438-8812. PMID 25575353. Check date values in: |date= (help)
  17. ↑ Kedia, Prashant; Tarnasky, Paul R.; Nieto, Jose; Steele, Stephen L.; Siddiqui, Ali; Xu, Ming-Ming; Tyberg, Amy; Gaidhane, Monica; Kahaleh, Michel (2018-04-17). "EUS-directed Transgastric ERCP (EDGE) Versus Laparoscopy-assisted ERCP (LA-ERCP) for Roux-en-Y Gastric Bypass (RYGB) Anatomy: A Multicenter Early Comparative Experience of Clinical Outcomes". Journal of Clinical Gastroenterology: 1. doi:10.1097/MCG.0000000000001037. ISSN 1539-2031. PMID 29668560.
  18. ↑ "pCLE".
  19. ↑ "PCLE tiny microscope".
  20. ↑ "confocal".
  21. ↑ "confocal diagnosis".
  22. ↑ Caillol, Fabrice; Filoche, Bernard; Gaidhane, Monica; Kahaleh, Michel (2013-6). "Refined probe-based confocal laser endomicroscopy classification for biliary strictures: the Paris Classification". Digestive Diseases and Sciences. 58 (6): 1784–1789. doi:10.1007/s10620-012-2533-5. ISSN 1573-2568. PMID 23314855. Check date values in: |date= (help)
  23. ↑ Kahaleh, Michel; Giovannini, Marc; Jamidar, Priya; Gan, S. Ian; Cesaro, Paola; Caillol, Fabrice; Filoche, Bernard; Karia, Kunal; Smith, Ioana (2015). "Probe-based confocal laser endomicroscopy for indeterminate biliary strictures: refinement of the image interpretation classification". Gastroenterology Research and Practice. 2015: 1–5. doi:10.1155/2015/675210. ISSN 1687-6121. PMC 4377502. PMID 25866506.
  24. ↑ 1040 Defining imaging criteria for indeterminate biliary strictures utilizing video cholangioscopy: The Monaco Classification. Sethi, Amrita; Shah, Raj J; Itoi, Takao; Moon, Jong Ho; Sejpal, Divyesh V   ; Pleskow, Douglas K.   ; Slivka, Adam   ; Adler, Douglas G.  ; Edmundowicz, Steven A.   ; Kim, Dong Choon   ; Petersen, Bret T; Gress, Frank G.  ; Gaidhane, Monica  ; Kahaleh, Michel. Volume 81, No. 5S : 2015 GASTROINTESTINAL ENDOSCOPY AB188. Digestive Diseases Week 2015
  25. ↑ Baisden, Joseph M.; Kahaleh, Michel; Weiss, Geoffrey R.; Sanfey, Hilary; Moskaluk, Christopher A.; Yeaton, Paul; de Lange, Eduard E.; Rich, Tyvin A. (2008-9). "Multimodality Treatment With Helical Tomotherapy Intensity Modulated Radiotherapy, Capecitabine, and Photodynamic Therapy is Feasible and Well Tolerated in Patients With Hilar Cholangiocarcinoma". Gastrointestinal Cancer Research: GCR. 2 (5): 219–224. ISSN 1934-7820. PMC 2632558. PMID 19259306. Check date values in: |date= (help)
  26. ↑ Kahaleh, Michel; Mishra, Rajnish; Shami, Vanessa M.; Northup, Patrick G.; Berg, Carl L.; Bashlor, Penny; Jones, Petra; Ellen, Kristi; Weiss, Geoffrey R. (2008-3). "Unresectable cholangiocarcinoma: comparison of survival in biliary stenting alone versus stenting with photodynamic therapy". Clinical Gastroenterology and Hepatology. 6 (3): 290–297. doi:10.1016/j.cgh.2007.12.004. ISSN 1542-7714. PMID 18255347. Check date values in: |date= (help)
  27. ↑ Gaidhane, Monica; Smith, Ioana; Ellen, Kristi; Gatesman, Jeremy; Habib, Nagy; Foley, Patricia; Moskaluk, Christopher; Kahaleh, Michel (2012). "Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of the Pancreas in a Porcine Model". Gastroenterology Research and Practice. 2012: 1–6. doi:10.1155/2012/431451. ISSN 1687-630X. PMC 3459266. PMID 23049547.
  28. ↑ Song, Tae Jun; Seo, Dong Wan; Lakhtakia, Sundeep; Reddy, Nageshwar; Oh, Dong Wook; Park, Do Hyun; Lee, Sang Soo; Lee, Sung Koo; Kim, Myung-Hwan (February 2016). "Initial experience of EUS-guided radiofrequency ablation of unresectable pancreatic cancer". Gastrointestinal Endoscopy. 83 (2): 440–443. doi:10.1016/j.gie.2015.08.048. ISSN 1097-6779. PMID 26344883.
  29. ↑ Shah, Raj J.; Shah, Janak N.; Waxman, Irving; Kowalski, Thomas E.; Sanchez-Yague, Andres; Nieto, Jose; Brauer, Brian C.; Gaidhane, Monica; Kahaleh, Michel (2015-4). "Safety and efficacy of endoscopic ultrasound-guided drainage of pancreatic fluid collections with lumen-apposing covered self-expanding metal stents". Clinical Gastroenterology and Hepatology. 13 (4): 747–752. doi:10.1016/j.cgh.2014.09.047. ISSN 1542-7714. PMID 25290534. Check date values in: |date= (help)
  30. ↑ Kahaleh, Michel; Gonzalez, Jean-Michel; Xu, Ming-Ming; Andalib, Iman; Gaidhane, Monica; Tyberg, Amy; Saumoy, Monica; Baptista Marchena, Alberto Jose; Barthet, Marc (2018-04-12). "Gastric peroral endoscopic myotomy for the treatment of refractory gastroparesis: a multicenter international experience". Endoscopy. doi:10.1055/a-0596-7199. ISSN 1438-8812. PMID 29649841.
  31. ↑ Perez-Miranda, Manuel; Tyberg, Amy; Poletto, Daniel; Toscano, Ernesto; Gaidhane, Monica; Desai, Amit P.; Kumta, Nikhil A.; Fayad, Lea; Nieto, Jose (2017 Nov/Dec). "EUS-guided Gastrojejunostomy Versus Laparoscopic Gastrojejunostomy: An International Collaborative Study". Journal of Clinical Gastroenterology. 51 (10): 896–899. doi:10.1097/MCG.0000000000000887. ISSN 1539-2031. PMID 28697151. Check date values in: |date= (help)
  32. ↑ Lopez-Nava, Gontrand; Sharaiha, Reem Z.; Vargas, Eric J.; Bazerbachi, Fateh; Manoel, Galvao Neto; Bautista-Castaño, Inmaculada; Acosta, Andres; Topazian, Mark D.; Mundi, Manpreet S. (10 2017). "Endoscopic Sleeve Gastroplasty for Obesity: a Multicenter Study of 248 Patients with 24 Months Follow-Up". Obesity Surgery. 27 (10): 2649–2655. doi:10.1007/s11695-017-2693-7. ISSN 1708-0428. PMID 28451929. Check date values in: |date= (help)
  33. ↑ Kumta, Nikhil A.; Saumoy, Monica; Tyberg, Amy; Kahaleh, Michel (2017-2). "Submucosal Tunneling Endoscopic Resection for En Bloc Removal of Large Esophageal Gastrointestinal Stromal Tumors". Gastroenterology. 152 (3): 482–483. doi:10.1053/j.gastro.2016.11.044. ISSN 1528-0012. PMID 27923727. Check date values in: |date= (help)
  34. ↑ Kumta, Nikhil A.; Xu, Ming-Ming; Marfatia, Pawan; Pittman, Meredith; Bednarek, Karl; Kahaleh, Michel (2016 0). "Submucosal tunneling endoscopic resection of a symptomatic leiomyoma in the proximal esophagus". Endoscopy. 48 (S 01): E398. doi:10.1055/s-0042-120705. ISSN 1438-8812. PMID 27997960. Check date values in: |date= (help)
  35. ↑ [michelkahaleh.com "Michel Kahaleh Website"] Check |url= value (help).
  36. ↑ "Founder".
  37. ↑ "TEUS Consortium".
  38. ↑ "Award".
  39. ↑ "Clinical excellence award".
  40. ↑ "Plenary session award".
  41. ↑ "Fellow NYSGE 2018".
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