Mucin 20

MUC20
Identifiers
AliasesMUC20, MUC-20, mucin 20, cell surface associated
External IDsMGI: 2385039 HomoloGene: 17135 GeneCards: MUC20
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q29Start195,720,882 bp[1]
End195,741,123 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

200958

224116

Ensembl

ENSMUSG00000035638

UniProt

Q8N307

Q8BUE7

RefSeq (mRNA)

NM_152673
NM_001098516
NM_001282506
NM_001291833
NM_020790

NM_001145874
NM_146071

RefSeq (protein)

NP_001269435
NP_001278762
NP_065841
NP_689886

NP_001139346
NP_666183

Location (UCSC)Chr 3: 195.72 – 195.74 MbChr 16: 32.78 – 32.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mucin-20 is a protein that in humans is encoded by the MUC20 gene.[5][6]

References

  1. 1 2 3 ENSG00000281630, ENSG00000277753, ENSG00000275501, ENSG00000275430, ENSG00000276583, ENSG00000278114, ENSG00000176945 GRCh38: Ensembl release 89: ENSG00000274843, ENSG00000281630, ENSG00000277753, ENSG00000275501, ENSG00000275430, ENSG00000276583, ENSG00000278114, ENSG00000176945 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035638 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Higuchi T, Orita T, Nakanishi S, Katsuya K, Watanabe H, Yamasaki Y, Waga I, Nanayama T, Yamamoto Y, Munger W, Sun HW, Falk RJ, Jennette JC, Alcorta DA, Li H, Yamamoto T, Saito Y, Nakamura M (Jan 2004). "Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney". J Biol Chem. 279 (3): 1968–79. doi:10.1074/jbc.M304558200. PMID 14565953.
  6. ↑ "Entrez Gene: MUC20 mucin 20, cell surface associated".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Higuchi T, Orita T, Katsuya K, et al. (2004). "MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met". Mol. Cell. Biol. 24 (17): 7456–68. doi:10.1128/MCB.24.17.7456-7468.2004. PMC 506992. PMID 15314156.
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
  • Li G, Zhang H, Lv J, et al. (2006). "Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin A nephropathy". Am. J. Nephrol. 26 (1): 43–9. doi:10.1159/000091785. PMID 16508246.


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