MTG1

MTG1
Identifiers
AliasesMTG1, GTP, GTPBP7, mitochondrial ribosome associated GTPase 1
External IDsMGI: 2685015 HomoloGene: 44527 GeneCards: MTG1
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10q26.3Start133,394,094 bp[1]
End133,421,307 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

92170

212508

Ensembl

ENSG00000148824

ENSMUSG00000039018

UniProt

Q9BT17

Q8R2R6

RefSeq (mRNA)

NM_138384

NM_199301

RefSeq (protein)

NP_612393

NP_955005

Location (UCSC)Chr 10: 133.39 – 133.42 MbChr 7: 140.14 – 140.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitochondrial GTPase 1 is an enzyme that in humans is encoded by the MTG1 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000148824 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039018 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. Barrientos A, Korr D, Barwell KJ, Sjulsen C, Gajewski CD, Manfredi G, Ackerman S, Tzagoloff A (Jun 2003). "MTG1 codes for a conserved protein required for mitochondrial translation". Mol Biol Cell. 14 (6): 2292–302. doi:10.1091/mbc.E02-10-0636. PMC 194879. PMID 12808030.
  6. "Entrez Gene: MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae)".

Further reading

  • Horisberger MA (1992). "Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins". J. Virol. 66 (8): 4705–9. PMC 241296. PMID 1629950.
  • Wilson AL, Sheridan KM, Erdman RA, Maltese WA (1996). "Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells". Biochem. J. 318 (3): 1007–14. doi:10.1042/bj3181007. PMC 1217717. PMID 8836150.
  • Tsai SC, Adamik R, Hong JX, et al. (1998). "Effects of arfaptin 1 on guanine nucleotide-dependent activation of phospholipase D and cholera toxin by ADP-ribosylation factor". J. Biol. Chem. 273 (33): 20697–701. doi:10.1074/jbc.273.33.20697. PMID 9694811.
  • Opdam FJ, Echard A, Croes HJ, et al. (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus". J. Cell Sci. 113 (15): 2725–35. PMID 10893188.
  • Gao X, Satoh T, Liao Y, et al. (2001). "Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras". J. Biol. Chem. 276 (45): 42219–25. doi:10.1074/jbc.M105760200. PMID 11524421.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Kuiperij HB, de Rooij J, Rehmann H, et al. (2003). "Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2". Biochim. Biophys. Acta. 1593 (2–3): 141–9. doi:10.1016/S0167-4889(02)00365-8. PMID 12581858.
  • Premzl M, Sangiorgio L, Strumbo B, et al. (2003). "Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein". Gene. 314: 89–102. doi:10.1016/S0378-1119(03)00707-8. PMID 14527721.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
  • Premzl M, Gready JE, Jermiin LS, et al. (2005). "Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysis". Mol. Biol. Evol. 21 (12): 2210–31. doi:10.1093/molbev/msh245. PMID 15342797.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.


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