METTL2B

METTL2B
Identifiers
AliasesMETTL2B, METL, METTL2, METTL2A, PSENIP1, methyltransferase like 2B
External IDsHomoloGene: 130696 GeneCards: METTL2B
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q32.1Start128,476,729 bp[1]
End128,506,602 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55798

n/a

Ensembl

ENSG00000165055

n/a

UniProt

Q6P1Q9

n/a

RefSeq (mRNA)

NM_018396

n/a

RefSeq (protein)

NP_060866

n/a

Location (UCSC)Chr 7: 128.48 – 128.51 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Methyltransferase-like protein 2B is an enzyme that in humans is encoded by the METTL2B gene.[3][4]

This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.[4]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000165055 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ Zhang SX, Guo Y, Boulianne GL (Dec 2001). "Identification of a novel family of putative methyltransferases that interact with human and Drosophila presenilins". Gene. 280 (1–2): 135–44. doi:10.1016/S0378-1119(01)00770-3. PMID 11738826.
  4. 1 2 "Entrez Gene: METTL2B methyltransferase like 2B".

Further reading

  • Zody MC, Garber M, Adams DJ, et al. (2006). "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage". Nature. 440 (7087): 1045–9. doi:10.1038/nature04689. PMC 2610434. PMID 16625196.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.


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