MEMO1

MEMO1
Identifiers
AliasesMEMO1, C2orf4, MEMO, NS5ATP7, CGI-27, mediator of cell motility 1
External IDsMGI: 1924140 HomoloGene: 6272 GeneCards: MEMO1
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2p22.3Start31,865,060 bp[1]
End32,011,230 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51072

76890

Ensembl

ENSG00000162959

ENSMUSG00000058704

UniProt

Q9Y316

Q91VH6

RefSeq (mRNA)

NM_001137602
NM_015955
NM_001301833
NM_001301852

NM_133771

RefSeq (protein)

NP_001131074
NP_001288762
NP_001288781
NP_057039

NP_598532

Location (UCSC)Chr 2: 31.87 – 32.01 MbChr 17: 74.2 – 74.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mediator of cell motility 1 is a protein that in humans is encoded by the MEMO1 gene.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000162959 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000058704 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. "Entrez Gene: Mediator of cell motility 1".

Further reading

  • Meira M, Masson R, Stagljar I, Lienhard S, Maurer F, Boulay A, Hynes NE (March 2009). "Memo is a cofilin-interacting protein that influences PLCgamma1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration". Journal of Cell Science. 122 (Pt 6): 787–97. doi:10.1242/jcs.032094. PMID 19223396.
  • Marone R, Hess D, Dankort D, Muller WJ, Hynes NE, Badache A (June 2004). "Memo mediates ErbB2-driven cell motility". Nature Cell Biology. 6 (6): 515–22. doi:10.1038/ncb1134. PMID 15156151.
  • Reymond A, Friedli M, Henrichsen CN, Chapot F, Deutsch S, Ucla C, Rossier C, Lyle R, Guipponi M, Antonarakis SE (November 2001). "From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map". Genomics. 78 (1–2): 46–54. doi:10.1006/geno.2001.6640. PMID 11707072.
  • Qiu C, Lienhard S, Hynes NE, Badache A, Leahy DJ (February 2008). "Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site". The Journal of Biological Chemistry. 283 (5): 2734–40. doi:10.1074/jbc.M703523200. PMID 18045866.
  • Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M (June 2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7: 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.
  • Zaoui K, Honoré S, Isnardon D, Braguer D, Badache A (November 2008). "Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells". The Journal of Cell Biology. 183 (3): 401–8. doi:10.1083/jcb.200805107. PMC 2575782. PMID 18955552.
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