MBOAT5

LPCAT3
Identifiers
AliasesLPCAT3, C3F, LPCAT, LPLAT 5, LPSAT, MBOAT5, OACT5, nessy, lysophosphatidylcholine acyltransferase 3
External IDsMGI: 1315211 HomoloGene: 14678 GeneCards: LPCAT3
EC number2.3.1.23
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12p13.31Start6,976,186 bp[1]
End7,018,510 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10162

14792

Ensembl

ENSG00000111684

ENSMUSG00000004270

UniProt

Q6P1A2

Q91V01

RefSeq (mRNA)

NM_005768

NM_145130

RefSeq (protein)

NP_005759

NP_660112

Location (UCSC)Chr 12: 6.98 – 7.02 MbChr 6: 124.66 – 124.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Lysophospholipid acyltransferase 5 is an enzyme that in humans is encoded by the LPCAT3 gene.[5][6][7][8] It is homologous to other membrane-bound O-acyltransferases.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000111684 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004270 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Ansari-Lari MA, Muzny DM, Lu J, Lu F, Lilley CE, Spanos S, Malley T, Gibbs RA (Sep 1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13". Genome Res. 6 (4): 314–26. doi:10.1101/gr.6.4.314. PMID 8723724.
  6. ↑ Ansari-Lari MA, Shen Y, Muzny DM, Lee W, Gibbs RA (May 1997). "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination". Genome Res. 7 (3): 268–80. doi:10.1101/gr.7.3.268. PMID 9074930.
  7. ↑ Zhao Y, Chen YQ, Bonacci TM, Bredt DS, Li S, Bensch WR, Moller DE, Kowala M, Konrad RJ, Cao G (Mar 2008). "Identification and characterization of a major liver lysophosphatidylcholine acyltransferase". J Biol Chem. 283 (13): 8258–65. doi:10.1074/jbc.M710422200. PMID 18195019.
  8. ↑ "Entrez Gene: MBOAT5 membrane bound O-acyltransferase domain containing 5".

Further reading

  • Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. doi:10.1038/nature04569. PMID 16541075.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Maurel-Zaffran C, Chauvet S, Jullien N, et al. (1999). "nessy, an evolutionary conserved gene controlled by Hox proteins during Drosophila embryogenesis". Mech. Dev. 86 (1–2): 159–63. doi:10.1016/S0925-4773(99)00105-7. PMID 10446276.


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