MARCH6

MARCH6
Identifiers
AliasesMARCH6, DOA10, MARCH-VI, RNF176, TEB4, membrane associated ring-CH-type finger 6
External IDsMGI: 2442773 HomoloGene: 4301 GeneCards: MARCH6
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5p15.2Start10,353,703 bp[1]
End10,440,388 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10299

223455

Ensembl

ENSG00000145495

ENSMUSG00000039100

UniProt

O60337

Q6ZQ89

RefSeq (mRNA)

NM_001270660
NM_001270661
NM_005885

NM_172606

RefSeq (protein)

NP_001257589
NP_001257590
NP_005876

NP_766194

Location (UCSC)Chr 5: 10.35 – 10.44 MbChr 15: 31.46 – 31.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

E3 ubiquitin-protein ligase MARCH6 is an enzyme that in humans is encoded by the MARCH6 gene.[5][6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000145495 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039100 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Fruh K (Jan 2004). "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins". J Virol. 78 (3): 1109–20. doi:10.1128/JVI.78.3.1109-1120.2004. PMC 321412. PMID 14722266.
  6. ↑ "Entrez Gene: MARCH6 membrane-associated ring finger (C3HC4) 6".

Further reading

  • Kreft SG, Wang L, Hochstrasser M (2006). "Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)". J. Biol. Chem. 281 (8): 4646–53. doi:10.1074/jbc.M512215200. PMID 16373356.
  • Hassink G, Kikkert M, van Voorden S, et al. (2005). "TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum". Biochem. J. 388 (Pt 2): 647–55. doi:10.1042/BJ20041241. PMC 1138973. PMID 15673284.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Swanson R, Locher M, Hochstrasser M (2001). "A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation". Genes Dev. 15 (20): 2660–74. doi:10.1101/gad.933301. PMC 312819. PMID 11641273.
  • Nagase T, Ishikawa K, Miyajima N, et al. (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.


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