MAB21L2

MAB21L2
Identifiers
AliasesMAB21L2, MCOPS14, Mab-21-like 2 (C. elegans), mab-21 like 2, MCSKS14
External IDsMGI: 1346022 HomoloGene: 7824 GeneCards: MAB21L2
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4q31.3Start150,581,922 bp[1]
End150,584,693 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10586

23937

Ensembl

ENSG00000181541

ENSMUSG00000057777

UniProt

Q9Y586

Q8BPP1

RefSeq (mRNA)

NM_006439

NM_011839

RefSeq (protein)

NP_006430

NP_035969

Location (UCSC)Chr 4: 150.58 – 150.58 MbChr 3: 86.55 – 86.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mab-21-like 2 (C. elegans) is a protein that in humans is encoded by the MAB21L2 gene.[5]

Function

This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181541 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000057777 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Mab-21-like 2 (C. elegans)".

Further reading

  • Mariani M, Baldessari D, Francisconi S, Viggiano L, Rocchi M, Zappavigna V, Malgaretti N, Consalez GG (December 1999). "Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development". Human Molecular Genetics. 8 (13): 2397–406. doi:10.1093/hmg/8.13.2397. PMID 10556287.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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