LEO1

LEO1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesLEO1, RDL, LEO1 homolog, Paf1/RNA polymerase II complex component
External IDsMGI: 2685031 HomoloGene: 133895 GeneCards: LEO1
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q21.2Start51,938,025 bp[1]
End51,971,806 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

123169

235497

Ensembl

ENSG00000166477

ENSMUSG00000042487

UniProt

Q8WVC0

Q5XJE5

RefSeq (mRNA)

NM_001286430
NM_138792
NM_001323903
NM_001323904

NM_001006122
NM_001039522

RefSeq (protein)

NP_001273359
NP_001310832
NP_001310833
NP_620147

NP_001034611

Location (UCSC)Chr 15: 51.94 – 51.97 MbChr 9: 75.44 – 75.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA polymerase-associated protein LEO1 is an enzyme that in humans is encoded by the LEO1 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000166477 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042487 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Rozenblatt-Rosen O, Hughes CM, Nannepaga SJ, Shanmugam KS, Copeland TD, Guszczynski T, Resau JH, Meyerson M (Jan 2005). "The Parafibromin Tumor Suppressor Protein Is Part of a Human Paf1 Complex". Mol Cell Biol. 25 (2): 612–20. doi:10.1128/MCB.25.2.612-620.2005. PMC 543415. PMID 15632063.
  6. ↑ "Entrez Gene: LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Zhao L, Tong T, Zhang Z (2005). "Expression of the Leo1-like domain of replicative senescence down-regulated Leo1-like (RDL) protein promotes senescence of 2BS fibroblasts". FASEB J. 19 (6): 521–32. doi:10.1096/fj.04-2689com. PMID 15791002.
  • Mosimann C, Hausmann G, Basler K (2006). "Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo". Cell. 125 (2): 327–41. doi:10.1016/j.cell.2006.01.053. PMID 16630820.
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


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