Kynurenine—glyoxylate transaminase

kynurenine-glyoxylate transaminase
Identifiers
EC number 2.6.1.63
CAS number 74506-33-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a kynurenine-glyoxylate transaminase (EC 2.6.1.63) is an enzyme that catalyzes the chemical reaction

L-kynurenine + glyoxylate 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

Thus, the two substrates of this enzyme are L-kynurenine and glyoxylate, whereas its two products are 4-(2-aminophenyl)-2,4-dioxobutanoate and glycine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-kynurenine:glyoxylate aminotransferase (cyclizing). This enzyme is also called kynurenine-glyoxylate aminotransferase.

References

    • Harada I (1980). "[Glucagen inducible kynurenine aminotransferase.]". Wakayama Igaku. 31: 61&ndash, 68.
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