Klaus Mosbach

Klaus Mosbach
Klaus Mosbach
Klaus Mosbach
Born 26 November 1932 (1932-11-26) (age 85)
Leipzig, Germany
Occupation Swedish biochemist

Klaus Mosbach is a Swedish biochemist. He is now professor emeritus at the department of pure and applied biochemistry of Lund University. He founded the Center for Molecular Imprinting in Lund, Sweden, .[1] He has also been co-founder of the Institute of biotechnology at ETH Zurich Switzerland 1982, .[2][3][4] He is a great visionary who gave shape to the modern era of Molecular imprinting for which he has been awarded the plaque at the international meeting of molecular imprinting in 2010 in New Orleans, United States of America.

Biography

Born1932, Leipzig, Germany.[5]
CitizenshipSwedish.[5]
FieldBiochemistry.[5]
InstitutionLund University, Sweden.[5]
other InstitutionETH Zurich.[5]
Known forMolecular imprinting, Enzyme immobilization, Affinity chromatography
Notable awardsEnzyme engineering award by Engineering foundation, USA.[6]

Gold medalist of Royal Swedish Academy of Engineering Sciences.[6]

Pierce Award by International organization of Affinity chromatography and Biorecognition.[7]

He is a great visionary who gave shape to the modern era of Molecular imprinting for which he has been awarded the plaque at the international meeting of molecular imprinting in 2010 in New Orleans, United States of America.[7]

Early life and education

Klaus Mosbach was born in Leipzig, Germany.[5][8] Family status: Married to May E., three daughters (Petra, Katja, Vanja)[5][8] Klaus Mosbach went to school in Leipzig Germany and Lund, Sweden, In 1952 moved to London, where he took Cambridge and interpreter exams.[8] After working in a pharmaceutical company, Ferrosan in Malmö, Sweden, he began his university studies at Lund University 1953. In 1956 he took his Master’s degree in chemistry and biology and subsequently in 1960 his Ph.D. in biochemistry with a thesis on "the biosynthesis of aromatic compounds in fungi and lichens".[9] He was then awarded the Waksman-Merck post-doctoral fellowship and stayed for 1.5 years at the Institute of Microbiology, Rutgers University, N.J., USA...[5][8] In 1962 he developed, jointly with Dr. Schaffner in the Philippines, a pasteurization process against Salmonella infections in coconuts, which subsequently was approved by the Food and Drug Administration and is presently used. After returning to Sweden, he continued his studies on secondary metabolism.[8] He received his second Ph.D. (corresponding to associate professorship or "Habilitation") from the University of Lund in 1964. Until 1970 he was associate professor there, and from 1970 onwards he has been full professor and head of the Department of Pure and Applied Biochemistry, which he founded, at Lund Institute of Technology. He also co-founded the Department of biotechnology at the Swiss Federal Institute of Technology ETH Zurich, Switzerland, in 1982.[4] He is now acting professor emeritus in the imprinting group Lund Institute of Technology.

Positions held

Professor Mosbach had leaves to take advantage of the following positions

During these stays he collaborated with Nobel Prize winners Lynen, Waksman as well as with Professors Estabrook and Srere, Katchalski-Katzir and Wilchek, Fukui, Chibata, Suzuki, Rees and Creighton respectively.[8]

Co-Workers

Klaus Mosbach had the pleasure of essentially wholly supervising more than sixty Ph.D.’s over the years...[8][12] A number of highly recognized scientists emerged from this pool, including the following professors C. Borrebaeck (in part), B.Sellergren (who is now a professor in Germany).[13] P. Brodelius, Leif Bulow, B. Danielsson, B. Hahn-Hägerdahl (in part), A.C. Koch. Schmidt, P.O. Larsson, C. F. Mandenius, B. Mattiasson, M.O. Månsson, I.A. Nicholls (starting as post doc), R. Ohlsson (in part), Lei Ye and S. Olsson working all in Sweden. To this a number of Professors working in other countries outside Sweden including, L.Fischer, K. Haupt, C.Lowe, H.Zhang should be added...[12][14] Klaus Mosbach has been collaborating with numerous companies over the years, including Biogen and later Hybritech, Eli Lilly, Igen, Hofman la Roche and has been involved in the formation of start-up companies by himself likewise former students of him have been successful in starting up companies like B.Ekberg, N.Siegbahn, Kurt Nilsson, Kjell Nilsson, Dariao Kriz. He is on the board of several journals and has been cited numerous times, such as in the International Who is Who and Who is Who in science and technology (millennium edition 2000/2001).[8][12]

Selected awards

  • Since 1981 member of the European Molecular Biology Organization (EMBO).[15]
  • Since 1982 honorary member of the American Society for Biochemistry and Molecular Biology.[10]
  • Received the Arrhenius Medal in 1983.[16]
  • Since 1985 member of the Protein Society, USA.
  • 1985 he was awarded two highly esteemed international scientific prizes given every second year, covering different major areas in biotechnology/biochemistry) as listed below:
  1. In Enzyme Engineering by the Engineering Foundation, New York, USA, "in recognition of outstanding contributions to the field of enzyme engineering".[6](previous winners: Dr. Chibata, subsequent to him Professors Katchalski-Katzir, Fukui, Klibanov, Lilly, Kula/Wandrey (jointly)).
  2. For "important contributions in the field of affinity chromatography" by the International Organization on Affinity Chromatography and Biorecognition (first winner K. Mosbach followed by M. Wilchek (1989), C.R. Lowe (1991), I.M. Chaiken (1993), J. Porath (1995), Regnier/Uhlén (1997) (jointly), Kasai (1999) and Vijayalaksmi (2001)...[6][17]
  • In 1990 he was awarded the gold medal of the Royal Swedish Academy of Engineering Sciences for his contribution to biotechnology, especially on the immobilization of bioactive substances.[6]
  • In 1993 he was awarded the research prize by the Swedish Fund for "Research without Animal Experiments".
  • In April 1999, Biogen Inc., together with its early members including Klaus Mosbach, received the US National Gold Medal of Technology. The recipient of this award was selected by the Department of Commerce and presented by the president William J. Clinton.[6]
  • In October 2002 at the International Symposium on Chromatography in London, Klaus Mosbach was presented the Martin Gold Medal, at the Royal Society, for the year 2000, by the Executive Committee of the Chromatographic Society. It was awarded him "in recognition of his major contributions to the field of separation science over many years". Previous recipients of this award are inter alia F. Regnier (1993), C. Horvath (1994) and W.H. Pirkle (1990).[18]
  • Mosbach has published more than 537 peer reviewed scientific articles and reviews with an H-Index of 77.[18][19]
  • He has written and edited four volumes of methods in enzymology series on Immobilized Enzymes, by Academic press (44,132,133,134).[18]
  • In addition he has received and applied for 84 patents.[18]

References

  1. ↑ Lacy, Sarah (July 21, 2006), "Do-It-Yourself Decaf", BusinessWeek
  2. ↑ ETH Zurich
  3. 1 2 "ETHistory - Page not found". ethz.ch.
  4. 1 2 "The Promise Of Molecular Imprinting". Scientific American. 295: 86–91. doi:10.1038/scientificamerican1006-86. Archived from the original on 2014-11-18. Retrieved 2015-06-19.
  5. 1 2 3 4 5 6 7 8 http://www.mendeley.com/research/molecularly-imprinted-polymers-biomimetic-sensors-1/#
  6. 1 2 3 4 5 6 "Biochemical Technology, Part A". Bokus.com.
  7. 1 2 "Awards". ismr.org. Retrieved 2015-06-19.
  8. 1 2 3 4 5 6 7 8 9 10 11 12 "Klaus Mosbach Homepage". Klaus Mosbach Homepage.
  9. ↑ "Biosynthesis of Lichen Substances, Products of a Symbiotic Association". Angewandte Chemie International Edition in English. 8: 240–250. doi:10.1002/anie.196902401.
  10. 1 2 3 4 "A Professional and Personal Odyssey". Journal of Biological Chemistry. 284: 19765–19780. doi:10.1074/jbc.X109.007518. PMC 2740401.
  11. 1 2 3 4 5 6 7 8 Haupt, Karsten; Mosbach, Klaus (2000-06-21). "Molecularly Imprinted Polymers and Their Use in Biomimetic Sensors". Chem. Rev. American Chemical Society. 100 (7): 2495–2504. doi:10.1021/cr990099w. Retrieved 2015-06-19.
  12. 1 2 3 "Biochemical Technology". google.com.
  13. ↑ "PD Dr. Börje Sellergren | AK Sellergren". Archived from the original on 2008-09-27. Retrieved 2015-06-19.
  14. ↑ "Klaus Mosbach Homepage". Klaus Mosbach Homepage.
  15. ↑ "masthead" (PDF). EMBO J. 1 (1). 1982. PMC 552983.
  16. ↑ "Mass spectrometry". Analytical Chemistry. pubs.acs.org. 58: 165–211. April 1986. doi:10.1021/ac00296a015. Retrieved 2015-06-19.
  17. ↑ "Awards". ismr.org.
  18. 1 2 3 4 http://www.lth.se/fileadmin/lth/omlth/kommunikation/lthnytt/lthn07_1.pdf
  19. ↑ http://www.klaus%5Bpermanent+dead+link%5D Mosbach.com
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