John C. Crabbe

John C. Crabbe
Nationality American
Education Stanford University
University of Colorado
Known for Mouse models of alcoholism
Awards 2015 Marlatt Mentorship Award from the Research Society on Alcoholism[1]
Scientific career
Fields Neuroscience
Institutions Oregon Health & Science University
Thesis Effects of D-amphetamine on learning and memory in inbred and hybrid mice (1973)
Doctoral advisor Herbert Alpern

John C. Crabbe, Jr. is an American neuroscientist and behavior geneticist. He is a professor of behavioral neuroscience at the Oregon Health & Science University (OHSU) School of Medicine, where he has worked since 1979.[2] He is also a senior research career scientist at the Veterans Affairs Medical Center in Portland, Oregon.[1] He is also the former director of OHSU's Portland Alcohol Research Center.[3][4]

Crabbe is known for his research using mouse models to study the pharmacogenetics of alcoholism.[3][5] He is also known for a 1999 study he and his colleagues published documenting significant variations in certain mouse behaviors across different labs, even when they all tried to follow the same protocols.[6][7][8] In 2011, he was chosen by the National Institute on Alcohol Abuse and Alcoholism to give the 16th annual Mark Keller Honorary Lecture.[2]

References

  1. 1 2 "Dual-appointed VA and SoM faculty set record for outside research support". Oregon Health & Science University (Press release). 2017-02-13. Retrieved 2018-06-29.
  2. 1 2 "Dr. Crabbe honored by National Institute on Alcohol Abuse and Alcoholism". Oregon Health & Science University (Press release). Retrieved 2018-06-29.
  3. 1 2 "John C. Crabbe, Ph.D." Oregon Health & Science University. Retrieved 2018-06-29.
  4. ↑ News, OHSU (2008-08-07). "OHSU Receives $1.3 Million Legacy to Advance Research into the Genetic Causes of Alcoholism". OHSU News (Press release). Retrieved 2018-06-29.
  5. ↑ Gordon, Serena (2002-05-15). "Gene Discovery May Help Explain Alcoholism". Consumer HealthDay. Retrieved 2018-06-29.
  6. ↑ Crabbe, John C.; Wahlsten, Douglas; Dudek, Bruce C. (1999-06-04). "Genetics of Mouse Behavior: Interactions with Laboratory Environment". Science. 284 (5420): 1670–1672. doi:10.1126/science.284.5420.1670. ISSN 0036-8075. PMID 10356397.
  7. ↑ Enserink, Martin (1999-06-03). "Fickle Mice Highlight Gene-Behavior Woes". Science. Retrieved 2018-06-29.
  8. ↑ Laursen, Lucas (2009-03-30). "Experimental design could reduce need for animal tests". Nature. doi:10.1038/news.2009.209. Retrieved 2018-06-29.


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