Isopropylbenzylamine

Isopropylbenzylamine
Names
	Preferred IUPAC name N-Benzylpropan-2-amine
	Other names N-(Phenylmethyl)propan-2-amine; Isopropylbenzylamine
Identifiers
CAS Number	102-97-6 ;
3D model (JSmol)	Interactive image;
ChemSpider	59415 ;
ECHA InfoCard	100.002.789
PubChem CID	66024;
	InChI InChI=1S/C10H15N/c1-9(2)11-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3 Key: LYBKPDDZTNUNNM-UHFFFAOYSA-N ; InChI=1/C10H15N/c1-9(2)11-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3 Key: LYBKPDDZTNUNNM-UHFFFAOYAR;
	SMILES N(C(C)C)Cc1ccccc1;
Properties
Chemical formula	C10H15N
Molar mass	149.24 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

Isopropylbenzylamine is a chemical compound used as an intermediate in the pharmaceutical industry as a precursor to the manufacture of some drugs. It has recently come to the attention of the DEA due to its use by illicit methamphetamine manufacturers as a diluting agent. This amine's hydrochloride salt is very similar in appearance and physical properties to methamphetamine and is cheap and not currently illegal. Isopropylbenzylamine is a structural isomer of methamphetamine, and has the same molar mass. Consequently it looks very similar to methamphetamine and has a similar melting point, and can be used to dilute methamphetamine without this being obvious to users, although some subtle differences such as slightly higher melting point and softer crystals may be apparent.^[1] Isopropylbenzylamine is not thought to have any stimulant effects in its own right, though anecdotal reports suggest that it may be associated with side effects such as headaches and confusion which are not typically associated with methamphetamine itself. The toxicity of N-isopropylbenzylamine has not been studied.^[2]^[3] Other "cutting agents" found to have been used for methamphetamine include the related compounds methylbenzylamine and ethylbenzylamine, as well as dimethylsulfone.^[4]^[5]

Isopropylbenzylammonium crystals seized by DEA.

References

↑ Sanderson RS. Identification of N-Methylbenzylamine Hydrochloride, N-Ethylbenzylamine Hydrochloride, and N-Isopropylbenzylamine Hydrochloride. Microgram Journal January–June 2008; 6(1-2)
↑ N-ISOPROPYLBENZYLAMINE HYDROCHLORIDE (AS “ICE” METHAMPHETAMINE MIMICS) ON THE WEST COAST. Microgram Bulletin, March 2008
↑ VERY LARGE SEIZURE OF N-ISOPROPYLBENZYLAMINE HYDROCHLORIDE IN BAKERSFIELD, CALIFORNIA. Microgram Bulletin, April 2008
↑ N-BENZYLMETHYLAMINE HCL AND N-BENZYLETHYLAMINE HCL ("ICE" AND CRYSTAL METHAMPHETAMINE MIMICS) IN THE SOUTHWEST. Microgram Bulletin, August 2007
↑ Weston, Robert G. (2010). "Quick Screening of Crystal Methamphetamine/Methyl Sulfone Exhibits by Raman Spectroscopy". Journal of Forensic Sciences. 55 (4): 1068–1075. doi:10.1111/j.1556-4029.2010.01336.x. ISSN 0022-1198.

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[1] Sanderson RS. Identification of N-Methylbenzylamine Hydrochloride, N-Ethylbenzylamine Hydrochloride, and N-Isopropylbenzylamine Hydrochloride. Microgram Journal January–June 2008; 6(1-2)

[2] N-ISOPROPYLBENZYLAMINE HYDROCHLORIDE (AS “ICE” METHAMPHETAMINE MIMICS) ON THE WEST COAST. Microgram Bulletin, March 2008

[3] VERY LARGE SEIZURE OF N-ISOPROPYLBENZYLAMINE HYDROCHLORIDE IN BAKERSFIELD, CALIFORNIA. Microgram Bulletin, April 2008

[4] N-BENZYLMETHYLAMINE HCL AND N-BENZYLETHYLAMINE HCL ("ICE" AND CRYSTAL METHAMPHETAMINE MIMICS) IN THE SOUTHWEST. Microgram Bulletin, August 2007

[5] Weston, Robert G. (2010). "Quick Screening of Crystal Methamphetamine/Methyl Sulfone Exhibits by Raman Spectroscopy". Journal of Forensic Sciences. 55 (4): 1068–1075. doi:10.1111/j.1556-4029.2010.01336.x. ISSN 0022-1198.