Intelectin-2

ITLN2
Identifiers
AliasesITLN2, HL-2, HL2, intelectin 2
External IDsHomoloGene: 135852 GeneCards: ITLN2
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q23.3Start160,945,025 bp[1]
End160,954,799 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

142683

n/a

Ensembl

ENSG00000158764

n/a

UniProt

Q8WWU7

n/a

RefSeq (mRNA)

NM_080878

n/a

RefSeq (protein)

NP_543154

n/a

Location (UCSC)Chr 1: 160.95 – 160.95 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.[3]

Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.[4]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000158764 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Entrez Gene: Intelectin 2". Retrieved 2016-02-25.
  4. Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT (March 2016). "Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition". The Journal of Biological Chemistry. 291 (11): 5596–610. doi:10.1074/jbc.M115.709212. PMC 4786701. PMID 26755729.
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