Immunoadsorption

Immunoadsorption is an alternative blood purification technique[1] used to eliminate pathogenic antibodies[2][3][4]

The technique shows results with rare side effects and a maximum elimination of pathogenic immunoglobulins from the blood.[1][5][6][7][8]

References

  1. 1 2 Koziolek, Michael J; Tampe, Desiree; Bähr, Matthias; Dihazi, Hassan; Jung, Klaus; Fitzner, Dirk; Klingel, Reinhard; Müller, Gerhard A; Kitze, Bernd (2012). "Immunoadsorption therapy in patients with multiple sclerosis with steroid-refractory optical neuritis". Journal of Neuroinflammation. 9: 80. doi:10.1186/1742-2094-9-80. PMC 3418188. PMID 22537481.
  2. ↑ Ikeda, Uichi; Kasai, Hiroki; Izawa, Atsushi; Koyama, Jun; Yazaki, Yoshikazu; Takahashi, Masafumi; Higuchi, Makoto; Koh, Chang-Sung; Yamamoto, Keiji (2008). "Immunoadsorption Therapy for Patients with Dilated Cardiomyopathy and Heart Failure". Current Cardiology Reviews. 4 (3): 219–22. doi:10.2174/157340308785160534. PMC 2780823. PMID 19936198.
  3. ↑ Hohenstein, B.; Bornstein, S.R.; Aringer, M. (2013). "Immunoadsorption for connective tissue disease". Atherosclerosis Supplements. 14 (1): 185–9. doi:10.1016/j.atherosclerosissup.2012.10.034. PMID 23357163.
  4. ↑ Terman, Davids.; Buffaloe, George; Cook, Gary; Sullivan, Michael; Mattioli, Carlos; Tillquist, Richard; Carlos Ayus, Juan (1979). "Extracorporeal Immunoadsorption: Initial Experience in Human Systemic Lupus Erythematosus". The Lancet. 314 (8147): 824. doi:10.1016/S0140-6736(79)92177-9.
  5. ↑ Griveas, Ioannis; Visvardis, Georgios; Skoura, L; Iniotaki, A; Papadopoulou, D; Sakellariou, G (2010). "Immunoadsorption in Highly-Sensitized Kidney Transplant Recipients". Balkan Military Medical Review. Periodical of Balkan Military Medical Committee. 13 (2): 47–50.
  6. ↑ HW Jr Snyder; Cochran, SK; Balint Jr, JP; Bertram, JH; Mittelman, A; Guthrie Jr, TH; Jones, FR (1992-05-01). "Experience with protein A-immunoadsorption in treatment-resistant adult immune thrombocytopenic purpura". Blood. 79 (9): 2237–45. PMID 1571540.
  7. ↑ Schneider, KM (1998). "Plasmapheresis and immunoadsorption: Different techniques and their current role in medical therapy". Kidney International Supplement. 64: S61–5. PMID 9475492.
  8. ↑ Schwenger, V.; Morath, C. (2010). "Immunoadsorption in nephrology and kidney transplantation". Nephrology Dialysis Transplantation. 25 (8): 2407. doi:10.1093/ndt/gfq264.

Further reading

  • Kandus, Aljoša; Ponikvar, Rafael; Buturović-Ponikvar, Jadranka; Bren, Andrej F.; Oblak, Manca; Mlinšek, Gregor; Kmetec, Andrej; Arnol, Miha (2013). "Plasmapheresis and Immunoadsorption for Treatment and Prophylaxis of Recurrent Focal Segmental Glomerulosclerosis in Adult Recipients of Deceased Donor Renal Grafts". Therapeutic Apheresis and Dialysis. 17 (4): 438–43. doi:10.1111/1744-9987.12093. PMID 23931886.
  • Amagai, Masayuki; Hashimoto, Takashi; Green, Kathleen J.; Shimizu, Nobuyoshi; Nishikawa, Takeji (1995). "Antigen-Specific Immunoadsorption of Pathogenic Autoantibodies in Pemphigus Foliaceus". Journal of Investigative Dermatology. 104 (6): 895–901. doi:10.1111/1523-1747.ep12606168. PMID 7539469.
  • Tyden, Gunnar; Kumlien, Gunilla; Genberg, Helena; Sandberg, John; Lundgren, Torbjorn; Fehrman, Ingela (2005). "ABO Incompatible Kidney Transplantations Without Splenectomy, Using Antigen-Specific Immunoadsorption and Rituximab". American Journal of Transplantation. 5 (1): 145–8. doi:10.1111/j.1600-6143.2004.00653.x. PMID 15636623.
  • Bensinger, William I.; Baker, Don A.; Buckner, C. D.; Clift, Reginald A.; Thomas, E. Donnall (1981). "Immunoadsorption for Removal of a and B Blood-Group Antibodies". New England Journal of Medicine. 304 (3): 160–2. doi:10.1056/NEJM198101153040308. PMID 7003388.


Immunoadsorption makes it possible to trap, or selectively remove, an antigen against which an antibody is directed from a mixture of antigens in solution. The opposite is also true-traping or selectively removing, the antigen-specific antibodies from a mixture of antibodies, using the specific antigen.



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