ITGB3BP

ITGB3BP
Identifiers
AliasesITGB3BP, CENP-R, CENPR, HSU37139, NRIF3, TAP20, integrin subunit beta 3 binding protein
External IDsMGI: 1914983 HomoloGene: 8617 GeneCards: ITGB3BP
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p31.3Start63,440,770 bp[1]
End63,593,721 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23421

67733

Ensembl

ENSG00000142856

ENSMUSG00000028549

UniProt

Q13352

Q9CQ82

RefSeq (mRNA)

NM_001206739
NM_014288
NM_001347145
NM_001347147
NM_001347148

NM_026348

RefSeq (protein)

NP_001193668
NP_001334074
NP_001334076
NP_001334077
NP_055103

NP_080624
NP_001349903
NP_001349904
NP_001349905

Location (UCSC)Chr 1: 63.44 – 63.59 MbChr 4: 99.77 – 99.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene.[5][6][7]

Interactions

ITGB3BP has been shown to interact with:

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000142856 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028549 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (December 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell Biol. 131 (3): 807–16. doi:10.1083/jcb.131.3.807. PMC 2120613. PMID 7593198.
  6. 1 2 3 Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (February 2000). "NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors". Mol Cell Biol. 19 (10): 7191–202. doi:10.1128/mcb.19.10.7191. PMC 84712. PMID 10490654.
  7. ↑ "Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)".
  8. ↑ Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (January 2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. 105 (1): 63–70. doi:10.1016/s0049-3848(01)00405-4. PMID 11864709.
  9. ↑ Ohtoshi A, Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (January 2000). "beta3-endonexin as a novel inhibitor of cyclin A-associated kinase". Biochem. Biophys. Res. Commun. 267 (3): 947–52. doi:10.1006/bbrc.1999.2007. PMID 10673397.
  10. ↑ Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M (October 2002). "Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081. PMID 12244126.
  11. 1 2 Li D, Wang F, Samuels HH (December 2001). "Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation". Mol. Cell. Biol. 21 (24): 8371–84. doi:10.1128/MCB.21.24.8371-8384.2001. PMC 100002. PMID 11713274.

Further reading

  • Kashiwagi H, Schwartz MA, Eigenthaler M, Davis KA, Ginsberg MH, Shattil SJ (1997). "Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail". J. Cell Biol. 137 (6): 1433–43. doi:10.1083/jcb.137.6.1433. PMC 2132534. PMID 9182673.
  • Tang S, Gao Y, Ware JA (1999). "Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein". J. Cell Biol. 147 (5): 1073–84. doi:10.1083/jcb.147.5.1073. PMC 2169340. PMID 10579726.
  • Ohtoshi A, Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (2000). "beta3-endonexin as a novel inhibitor of cyclin A-associated kinase". Biochem. Biophys. Res. Commun. 267 (3): 947–52. doi:10.1006/bbrc.1999.2007. PMID 10673397.
  • Li D, Wang F, Samuels HH (2001). "Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation". Mol. Cell. Biol. 21 (24): 8371–84. doi:10.1128/MCB.21.24.8371-8384.2001. PMC 100002. PMID 11713274.
  • Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. 105 (1): 63–70. doi:10.1016/S0049-3848(01)00405-4. PMID 11864709.
  • Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M (2003). "Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081. PMID 12244126.
  • Li D, Das S, Yamada T, Samuels HH (2004). "The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells". Mol. Cell. Biol. 24 (9): 3838–48. doi:10.1128/MCB.24.9.3838-3848.2004. PMC 387764. PMID 15082778.
  • Talukder AH, Gururaj A, Mishra SK, Vadlamudi RK, Kumar R (2004). "Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator". Mol. Cell. Biol. 24 (15): 6581–91. doi:10.1128/MCB.24.15.6581-6591.2004. PMC 444867. PMID 15254226.
  • Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR, Cleveland DW (2006). "The human CENP-A centromeric nucleosome-associated complex". Nat. Cell Biol. 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
  • Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR, Desai A, Fukagawa T (2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat. Cell Biol. 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.