Hydroxypyruvate isomerase

hydroxypyruvate isomerase
Identifiers
EC number 5.3.1.22
CAS number 74812-48-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a hydroxypyruvate isomerase (EC 5.3.1.22) is an enzyme that catalyzes the chemical reaction

hydroxypyruvate 2-hydroxy-3-oxopropanoate

Hence, this enzyme has one substrate, hydroxypyruvate, and one product, 2-hydroxy-3-oxopropanoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is hydroxypyruvate aldose-ketose-isomerase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

    • de Windt FE, van der Drift C (1980). "Purification and some properties of hydroxypyruvate isomerase of Bacillus fastidiosus". Biochim. Biophys. Acta. 613 (2): 556&ndash, 62. doi:10.1016/0005-2744(80)90111-4. PMID 7448201.


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