Hydroxyacid oxidase 2

HAO2
Identifiers
AliasesHAO2, GIG16, HAOX2, hydroxyacid oxidase 2
External IDsMGI: 96012 HomoloGene: 97412 GeneCards: HAO2
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p12Start119,368,779 bp[1]
End119,394,130 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51179

56185

Ensembl

ENSG00000116882

ENSMUSG00000027870

UniProt

Q9NYQ3

Q9NYQ2

RefSeq (mRNA)

NM_001005783
NM_016527

NM_019545

RefSeq (protein)

NP_001005783
NP_057611

NP_062418

Location (UCSC)Chr 1: 119.37 – 119.39 MbChr 3: 98.87 – 98.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Hydroxyacid oxidase 2 is a protein that in humans is encoded by the HAO2 gene. [5]

Function

This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000116882 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027870 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Hydroxyacid oxidase 2". Retrieved 2016-07-03.

Further reading

  • Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N (2010). "Genetic susceptibility to distinct bladder cancer subphenotypes". Eur. Urol. 57 (2): 283–92. doi:10.1016/j.eururo.2009.08.001. PMC 3220186. PMID 19692168.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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