Huang Minlon

Huang Minlon or Huang Minglong (simplified Chinese: 黄鸣龙; traditional Chinese: 黃鳴龍; 3 July 1898 – 1 July 1979) was a Chinese organic chemist and pharmaceutical scientist. Huang is considered as a pioneer and founder of modern pharmaceutical industries in China.[1]

Life

Huang was born in Yangzhou, Jiangsu Province on 3 July 1898, during the late Qing dynasty. In 1917, Huang graduated from Yangzhou Middle School. In 1918, Huang graduated from the Zhejiang Provincial College of Medicine (current Zhejiang University School of Medicine).[2]

In 1924, Huang obtained PhD from the University of Berlin, Germany. In 1925, Huang went back to China and became a professor and later department head at Zhejiang Provincial College of Medicine. From 1934 to 1940, Huang worked in research in Germany and the UK.

Huang returned to China in 1940 and became a senior researcher at Academia Sinica. Huang was also a professor at the National Southwestern Associated University.

During 1945-1952, Huang was a visiting professor at Harvard University in the US. Huang also visited the Merck & Co..

In 1952, Huang returned to China. He served as the Chair of Department of Chemistry, Academy of Military Medical Sciences of PLA. Huang was also a senior researcher at the Shanghai Institute of Organic Chemistry (SIOC) of the Chinese Academy of Sciences.

Huang is regarded as one of pioneers and founders of modern pharmaceutical industries in China. Huang was a senior academician at the Chinese Academy of Sciences (1955 election). Huang was the Vice-president and later became the Honorary-president of the Chinese Society for Pharmaceutical Sciences (a.k.a. Chinese Pharmaceutical Association).

Huang published more than 100 papers, in both English and Chinese.

Huang-Minlon modification

The Huang Modification or Huang-Minlon Modification[3][4] is named after Huang Minlon. It was the first time that a Chinese name appeared in an organic chemical reaction.

It's a short-cut for the Wolff-Kishner reduction and involves heating the carbonyl compound, potassium hydroxide, and hydrazine hydrate together in ethylene glycol in a one-pot reaction.[5] Huang devised this modified synthesis in 1945 while he was in the United States.

In many sources, it's also mentioned such method as Wolff-Kishner-Huang Reduction (or Wolff-Kishner-Huang Minlon method/reaction/reduction), or in German Wolff-Kishner/Huang-Minlon Reduktion (or Wolff-Kishner-Huang-Minlon-Reduktion).

References

  1. ↑ 百度百科 黄鸣龙 简介
  2. ↑ Huang Minlon's CV Archived 2008-09-15 at the Wayback Machine.
  3. ↑ Huang-Minlon J. Am. Chem. Soc. 1946, 68, 2487.
  4. ↑ Huang-Minlon J. Am. Chem. Soc. 1949, 71, 3301.
  5. ↑ Organic Syntheses, Coll. Vol. 4, p.510 (1963); Vol. 38, p.34 (1958)
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