Homophthalic acid

Homophthalic acid
Names
	IUPAC name 2-(Carboxymethyl)benzoic acid
	Other names α-Carboxy-o-toluic acid; Carboxyphenyl acetic acid
Identifiers
CAS Number	89-51-0;
3D model (JSmol)	Interactive image;
ChemSpider	60010 ;
ECHA InfoCard	100.001.740
	InChI InChI=1S/C9H8O4/c10-8(11)5-6-3-1-2-4-7(6)9(12)13/h1-4H,5H2,(H,10,11)(H,12,13) Key: ZHQLTKAVLJKSKR-UHFFFAOYSA-N[1];
	SMILES OC(=O)C1=CC=CC=C1CC(O)=O;
Properties
Chemical formula	C9H8O4
Molar mass	180.16 g·mol−1
Appearance	Off-white to light yellow or pale green
Melting point	181 °C (358 °F; 454 K) [2]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Homophthalic acid is a dicarboxylic acid with the formula C₆H₄(CO₂H)CH₂CO₂H. It is a colorless solid. The compounds can be prepared by the Willgerodt reaction from 2-acetylbenzoic acid.^[3]

One of the uses is in the preparation of the NSAID tesicam.

References

↑ Index
↑ Homophthalic Acid | C9H8O4 | Chemspider
↑ Schwenk, Erwin; Papa, Domenick "Preparation of aryl aliphatic acids by the modified Willgerodt reaction" Journal of Organic Chemistry (1946), 11, 798-802. doi:10.1021/jo01176a023

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

Names

IUPAC name 2-(Carboxymethyl)benzoic acid
Other names α-Carboxy-o-toluic acid Carboxyphenyl acetic acid
Identifiers
CAS Number	89-51-0
3D model (JSmol)	Interactive image
ChemSpider	60010^Y
ECHA InfoCard	100.001.740
InChI InChI=1S/C9H8O4/c10-8(11)5-6-3-1-2-4-7(6)9(12)13/h1-4H,5H2,(H,10,11)(H,12,13) Key: ZHQLTKAVLJKSKR-UHFFFAOYSA-N^[1]
SMILES OC(=O)C1=CC=CC=C1CC(O)=O
Properties
Chemical formula	C₉H₈O₄
Molar mass	180.16 g·mol⁻¹
Appearance	Off-white to light yellow or pale green
Melting point	181 °C (358 °F; 454 K) ^[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references