Harvey Berger

Harvey Berger
Born (1950-06-06) June 6, 1950
Residence Palm Beach, Florida, U.S.
Alma mater Colgate University, Yale School of Medicine
Occupation Executive Chairman at Medinol, Inc.
Board member of Dana-Farber Cancer Institute

Harvey J. Berger, M.D. is an American physician-scientist, entrepreneur, philanthropist, and biotechnology executive. He is the Founder, Chairman and CEO Emeritus of ARIAD Pharmaceuticals, Inc. and Executive Chairman at Medinol, Inc.

Early life and education

Berger received his A.B. in Biology from Colgate University in 1972 and received his M.D. from Yale School of Medicine in 1977.[1][2] He completed further medical and research training at the Massachusetts General Hospital and Yale-New Haven Hospital.[2]

Career

From 1986 until 1991, Berger held executive management positions at Centocor, Inc. including Executive Vice President and President of the Research and Development Division.[3] He led the development of Remicade® (infliximab), formerly known as Centara, a drug for the treatment of autoimmune diseases such as Crohn’s disease, ulcerative colitis and rheumatoid arthritis, ReoPro® (abciximab), formerly known as CentoRx, a drug for the prevention of ischemic complications in patients with CAD undergoing percutaneous interventions,[4][5] and the cancer diagnostic test, CA125, to evaluate patients with ovarian cancer.[6][7]

In 1991, Berger founded ARIAD Pharmaceuticals in Cambridge, Massachusetts.[8][9] He served as Chairman and CEO from 1991 to 2015.[9][2] In 1992, ARIAD raised $46 million, the largest single round of financing for a startup in the biotechnology industry at the time.[10][11] ARIAD’s plan was to develop drugs that would interfere with communication signals within cells, rather than on the cell surface or in between cells.[10] In 1994, ARIAD filed for an initial public offering and was listed on the NASDAQ market.[12][13]

In 2000, Berger focused ARIAD on oncology, based on recent discoveries in the human genome.[11][14] Under Berger’s leadership, ARIAD grew to over 365 employees and established a European headquarters in Lausanne, Switzerland.[15][16]

While Berger was CEO, ARIAD developed five new medicines including the blood-cancer drug Iclusig, Brigatinib, a potential lung cancer treatment and AP37288, for lung cancer with novel mutated genetic targets.[9][17]

At the end of 2015, Berger retired from ARIAD and became an advisor to the board of directors.[9][18] In early 2017, ARIAD was acquired by Takeda Pharmaceuticals, Ltd. for $5.2 billion, becoming part of Takeda Oncology.[19]

In February 2017, Medinol, Inc. announced that Berger would be serving as its Executive Chairman.[20] On the global management team, his focuses at Medinol would include business management, global strategy, new business and technology initiatives, as well as improving operational efficiency as the company expands worldwide.[21][3] Berger’s role at Medinol was said to include working with their core business of interventional cardiovascular devices, along with its new businesses developing percutaneous aortic valves, sub-millimeter implantable sensors, and related products.[21]

Berger has held senior academic and administrative roles at Emory University, Yale University and the University of Pennsylvania.[3][21] He was also a member of the Dean’s Council of Yale University School of Medicine.[2] During his time at Emory, Berger led a program for developing cardiovascular single-photon emission computed tomographic (SPECT) imaging, supported by General Electric Medical Systems.[22] He and other colleagues at Emory collaborated on the development of new quantitative techniques for cardiac SPECT imaging.[23]

Berger has contributed to a wide range of medical journals including the New England Journal of Medicine and American Journal of Cardiology,[24][25] and has been interviewed by Fox Business[26][27][28][29] and CNBC.[30] He was also an established investigator of the American Heart Association.[3]

Awards

In 2013, Berger was awarded the Ernst & Young Entrepreneur of the Year Award for the New England Region. The award recognizes success in innovation, financial performance, personal commitment to their business communities and other areas.[31] In the same year, Berger was awarded the Gold Stevie Award as Executive of the Year, Pharmaceuticals.[32][33]

Personal life and philanthropy

Berger resides in Palm Beach, Florida with his wife Chrysanthi and their two daughters, Isabella Grace Berger and Nicole Elizabeth Berger.[34][35] His daughter Nicole has appeared in several movies including Two for One.[36] Chrysanthi Berger (née Casseres)[37] attended Laguardia High School of Music and Art and was the concertmaster there. She earned a Master's Degree from the Manhattan School of Music.[38]

Harvey and Chrysanthi Berger have supported the Palm Beach Day Academy and the American Cancer Society.[39][40] In February 2018, Berger was appointed to the Dana-Farber Cancer Institute Board of Trustees, the governing board of the organization.[41]

References

  1. ↑ "A showcase of alumni talent (The Colgate Scene, September 2002)". www4.colgate.edu. Retrieved 2017-09-25.
  2. 1 2 3 4 "MIT Sloan BioInnovations 2011". web.mit.edu. Retrieved 2017-09-20.
  3. 1 2 3 4 Bader, Emily (2017-02-16). "Medinol appoints executive chairman of Medinol US | NJBIZ". NJBIZ. Retrieved 2017-09-23.
  4. ↑ Letter, The Pharma. "US Approval For Centocor's ReoPro - Pharmaceutical industry news". www.thepharmaletter.com. Retrieved 2017-09-25.
  5. ↑ "Biotechnology Report, Medicines in Development, 2006 | Interleukin 2 | Monoclonal Antibody". Scribd. Retrieved 2017-09-25.
  6. ↑ "Centocor CA 125 II, New Version of CA 125 Assay, Is Now Available | Cancer Network". www.cancernetwork.com. Retrieved 2018-03-20.
  7. ↑ Matsukura, A.; Nakazawa, Y.; Hama, S. (November 1989). "[A shortened method for the assay with Centocor radioimmunoassay kit]". Radioisotopes. 38 (11): 469–472. ISSN 0033-8303. PMID 2595020.
  8. ↑ "Ariad moving to new Kendall Square headquarters - The Boston Globe". BostonGlobe.com. Retrieved 2017-09-24.
  9. 1 2 3 4 "Former Ariad CEO Berger says Takeda deal was 'merely a matter of time'". www.bizjournals.com. Retrieved 2017-09-24.
  10. 1 2 Pollack, Rew (1992-03-27). "COMPANY NEWS; Ariad Raises $46 Million In Placement". The New York Times. ISSN 0362-4331. Retrieved 2017-09-25.
  11. 1 2 "ARIAD Pharmaceuticals | Stevie Awards". stevieawards.com. Retrieved 2017-09-25.
  12. ↑ "Equity Issues This Week". The New York Times. 1994-05-16. ISSN 0362-4331. Retrieved 2017-09-25.
  13. ↑ "Ariad Pharmaceuticals, Inc. (ARIA) Stock Higher on Takeda Buyout News". NASDAQ.com. 2017-01-09. Retrieved 2017-09-25.
  14. ↑ "Interview: Harvey Berger and Timothy Clackson, Ariad". www.pmlive.com. 2013-10-14. Retrieved 2017-09-20.
  15. ↑ "Ariad's Harvey Berger says he's 'absolutely' secure in his role as CEO". www.bizjournals.com. Retrieved 2017-09-25.
  16. ↑ "Ariad sells European operations for $140M upfront plus royalties". www.bizjournals.com. Retrieved 2017-09-25.
  17. ↑ "Positive Preclinical Results for Lung Cancer Drug Announced at Annual Meeting of Cancer Research - Lung Disease News". Lung Disease News. 2016-04-22. Retrieved 2017-09-24.
  18. ↑ "ARIAD Founder, Harvey J. Berger, M.D., to Retire as Chairman and Chief Executive Officer". ARIAD Pharmaceuticals, Inc. Retrieved 2017-09-24.
  19. ↑ "Former Ariad CEO Berger says Takeda deal was 'merely a matter of time'". www.bizjournals.com. Retrieved 2017-09-23.
  20. ↑ "Berger named to post at Medinol - The Boston Globe". BostonGlobe.com. Retrieved 2017-09-25.
  21. 1 2 3 "Medinol hires Harvey Berger as executive chairman of its US operations". Cardiovascular Business. Retrieved 2017-09-23.
  22. ↑ DePasquale, E. E.; Nody, A. C.; DePuey, E. G.; Garcia, E. V.; Pilcher, G.; Bredlau, C.; Roubin, G.; Gober, A.; Gruentzig, A. (1988-02-01). "Quantitative rotational thallium-201 tomography for identifying and localizing coronary artery disease". Circulation. 77 (2): 316–327. doi:10.1161/01.CIR.77.2.316. ISSN 0009-7322. PMID 3257422.
  23. ↑ Berger, Harvey J.; Eisner, Robert; DePuey, E. Gordon; Patterson, Randolph (1984-11-01). "New Vistas in Cardiovascular Nuclear Medicine". Journal of Nuclear Medicine. 25 (11): 1254–1258. ISSN 0161-5505. PMID 6333498.
  24. ↑ Ziegler, Elizabeth J.; Fisher, Charles J.; Sprung, Charles L.; Straube, Richard C.; Sadoff, Jerald C.; Foulke, Garrett E.; Wortel, Cornelis H.; Fink, Mitchell P.; Dellinger, R. Phillip. "Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin". New England Journal of Medicine. 324 (7): 429–436. doi:10.1056/nejm199102143240701.
  25. ↑ Johnstone, David E.; Sands, Milton J.; Berger, Harvey J.; Reduto, Lawrence A.; Lachman, Anthony S.; Wackers, Frans J. Th; Cohen, Lawrence S.; Gottschalk, Alexander; Zaret, Barry L. (1980-06-01). "Comparison of exercise radionuclide angiocardiography and thallium-201 myocardial perfusion imaging in coronary artery disease". American Journal of Cardiology. 45 (6): 1113–1119. doi:10.1016/0002-9149(80)90467-1. ISSN 0002-9149. PMID 7377108.
  26. ↑ "Ariad CEO on Developing New Drugs". Fox Business. 2011-07-15. Retrieved 2017-11-10.
  27. ↑ "Ariad CEO on the Three Drugs in the Pipeline for Cancer Treatment". Fox Business. 2011-11-10. Retrieved 2017-11-10.
  28. ↑ "Ariad Pharmaceuticals Working on Cancer 'Miracle Pill'". Fox Business. 2012-08-03. Retrieved 2017-11-10.
  29. ↑ "Ariad Pharmaceuticals CEO on a New Leukemia Drug". Fox Business. 2012-06-08. Retrieved 2017-11-10.
  30. ↑ Chang, Kirsten (2012-06-04). "Cramer Interviews Ariad Pharma CEO". CNBC. Retrieved 2017-11-10.
  31. ↑ Staff, AOL. "ARIAD Chief Executive Officer, Harvey J. Berger, M.D., Recognized as 2013 Ernst & Young Entrepreneur". AOL.com. Retrieved 2017-09-21.
  32. ↑ Wire, Business (2013-06-18). "ARIAD Honored With Gold Stevie® Awards As Pharmaceutical Company Of The Year At 2013 American Business Awardssm". TheStreet. Retrieved 2017-09-25.
  33. ↑ "Life Sciences & Pharmaceuticals CEO Symposium". www.yjp.org. Retrieved 2017-09-25.
  34. ↑ "Palm Beach 13-year-old gets Broadway bash — and a visit from Flo Rida". palmbeachdailynews. Retrieved 2017-09-23.
  35. ↑ "Alumni > Autumn 2008 | Yale Medicine". ymm.yale.edu. Retrieved 2017-11-10.
  36. ↑ king-theme.com. "TWO FOR ONE: Buffalo Debut November 4th at Buffalo Dreams Festival". www.filmbuffaloniagara.com. Retrieved 2017-09-23.
  37. ↑ "PET-OWNING & PARENTING". New York Post. 2003-08-17. Retrieved 2017-11-10.
  38. ↑ "Nicole Elizabeth Berger Debuts Film Two for One at Napa Film Festival". I Heart Heels. 2016-11-12. Retrieved 2017-11-10.
  39. ↑ "'Jukebox Hero' Gramm brings '80s to life for American Cancer Society". palmbeachdailynews. Retrieved 2017-11-10.
  40. ↑ "MAD, PMP, HSS, and PBDA". New York Social Diary. 2017-03-20. Retrieved 2017-11-10.
  41. ↑ "Dana-Farber Cancer Institute appoints six new members to Board of Trustees - Dana-Farber Cancer Institute | Boston, MA". www.dana-farber.org. Retrieved 2018-03-20.
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