Glutamine N-phenylacetyltransferase

glutamine N-phenylacetyltransferase
Identifiers
EC number 2.3.1.14
CAS number 9030-00-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a glutamine N-phenylacetyltransferase (EC 2.3.1.14) is an enzyme that catalyzes the chemical reaction

phenylacetyl-CoA + L-glutamine CoA + alpha-N-phenylacetyl-L-glutamine

Thus, the two substrates of this enzyme are phenylacetyl-CoA and L-glutamine, whereas its two products are CoA and alpha-N-phenylacetyl-L-glutamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase. Other names in common use include glutamine phenylacetyltransferase, and phenylacetyl-CoA:L-glutamine N-acetyltransferase. This enzyme participates in tyrosine metabolism and phenylalanine metabolism.

References

    • Moldave K; Meister A (1957). "Synthesis of phenylacetylglutamine by human tissue". J. Biol. Chem. 229 (1): 463&ndash, 476. PMID 13491597.
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