GSG2

HASPIN
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHASPIN, GSG2, germ cell associated 2, haspin, histone H3 associated protein kinase
External IDsMGI: 1194498 HomoloGene: 49236 GeneCards: HASPIN
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17p13.2Start3,723,903 bp[1]
End3,726,699 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

83903

14841

Ensembl

ENSG00000177602

ENSMUSG00000050107

UniProt

Q8TF76

Q9Z0R0

RefSeq (mRNA)

NM_031965

NM_010353

RefSeq (protein)

NP_114171

NP_034483

Location (UCSC)Chr 17: 3.72 – 3.73 MbChr 11: 73.14 – 73.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase haspin is an enzyme that in humans is encoded by the GSG2 gene.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000177602 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050107 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: GSG2 germ cell associated 2 (haspin)".

Further reading

  • Dai J, Sullivan BA, Higgins JM (2007). "Regulation of mitotic chromosome cohesion by Haspin and Aurora B.". Dev. Cell. 11 (5): 741–50. doi:10.1016/j.devcel.2006.09.018. PMID 17084365.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Dai J, Sultan S, Taylor SS, Higgins JM (2005). "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment". Genes Dev. 19 (4): 472–88. doi:10.1101/gad.1267105. PMC 548948. PMID 15681610.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Higgins JM (2001). "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells". Gene. 267 (1): 55–69. doi:10.1016/S0378-1119(01)00387-0. PMID 11311556.
  • Tanaka H, Iguchi N, Nakamura Y, et al. (2001). "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase". Mol. Hum. Reprod. 7 (3): 211–8. doi:10.1093/molehr/7.3.211. PMID 11228240.


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