GPM6A

GPM6A
Identifiers
AliasesGPM6A, GPM6, M6A, glycoprotein M6A
External IDsMGI: 107671 HomoloGene: 3864 GeneCards: GPM6A
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4q34.2Start175,632,934 bp[1]
End176,002,664 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

2823

234267

Ensembl

ENSG00000150625

ENSMUSG00000031517

UniProt

P51674

P35802

RefSeq (mRNA)

NM_001261447
NM_001261448
NM_005277
NM_201591
NM_201592

NM_001253754
NM_001253756
NM_153581

RefSeq (protein)

NP_001248376
NP_001248377
NP_005268
NP_963885
NP_963886

NP_001240683
NP_001240685
NP_705809

Location (UCSC)Chr 4: 175.63 – 176 MbChr 8: 54.95 – 55.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene.[5][6][7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000150625 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031517 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Olinsky S, Loop BT, DeKosky A, Ripepi B, Weng W, Cummins J, Wenger SL, Yan Y, Lagenaur C, Narayanan V (Sep 1996). "Chromosomal mapping of the human M6 genes". Genomics. 33 (3): 532–6. doi:10.1006/geno.1996.0231. PMID 8661015.
  6. ↑ Liang YJ, Wu DF, Stumm R, Hollt V, Koch T (Jul 2008). "Membrane glycoprotein M6A promotes mu-opioid receptor endocytosis and facilitates receptor sorting into the recycling pathway". Cell Res. 18 (7): 768–79. doi:10.1038/cr.2008.71. PMID 18574501.
  7. ↑ "Entrez Gene: GPM6A glycoprotein M6A".

Further reading

  • Boks MP, Hoogendoorn M, Jungerius BJ, et al. (2008). "Do mood symptoms subdivide the schizophrenia phenotype? association of the GMP6A gene with a depression subgroup". American Journal of Medical Genetics. 147B (6): 707–11. doi:10.1002/ajmg.b.30667. PMID 18163405.
  • DeGiorgis JA, Jaffe H, Moreira JE, et al. (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". J. Proteome Res. 4 (2): 306–15. doi:10.1021/pr0498436. PMID 15822905.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Shin BK, Wang H, Yim AM, et al. (2003). "Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function". J. Biol. Chem. 278 (9): 7607–16. doi:10.1074/jbc.M210455200. PMID 12493773.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Mukobata S, Hibino T, Sugiyama A, et al. (2002). "M6a acts as a nerve growth factor-gated Ca(2+) channel in neuronal differentiation". Biochem. Biophys. Res. Commun. 297 (4): 722–8. doi:10.1016/S0006-291X(02)02284-2. PMID 12359212.
  • Shimizu F, Watanabe TK, Fujiwara T, et al. (1996). "Isolation and mapping of the human glycoprotein M6 gene (GPM6A) to 4q33→q34". Cytogenet. Cell Genet. 74 (1–2): 138–9. doi:10.1159/000134401. PMID 8893821.
  • Yan Y, Narayanan V, Lagenaur C (1996). "Expression of members of the proteolipid protein gene family in the developing murine central nervous system". J. Comp. Neurol. 370 (4): 465–78. doi:10.1002/(SICI)1096-9861(19960708)370:4<465::AID-CNE4>3.0.CO;2-2. PMID 8807448.


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