GFRAL

GFRAL
Identifiers
Aliases	GFRAL, C6orf144, GRAL, UNQ9356, bA360D14.1, GDNF family receptor alpha like
External IDs	MGI: 3607786 HomoloGene: 45748 GeneCards: GFRAL
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	55,402,493 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	76,213,657 bp[2]
Gene ontology
Molecular function	• signaling receptor activity; • protein binding; • glial cell-derived neurotrophic factor receptor activity; • receptor tyrosine kinase binding;
Cellular component	• integral component of membrane; • plasma membrane; • intracellular; • membrane; • external side of plasma membrane; • receptor complex;
Biological process	• negative regulation of neuron apoptotic process; • stress-activated protein kinase signaling cascade; • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; • activation of MAPK activity; • reduction of food intake in response to dietary excess; • glial cell-derived neurotrophic factor receptor signaling pathway; • positive regulation of MAPK cascade; • positive regulation of protein kinase B signaling; • nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	389400
	404194
	ENSG00000187871
	ENSMUSG00000059383
	Q6UXV0
	Q6SJE0
	NM_207410
	NM_205844
	NP_997293
	NP_995316
	Wikidata
View/Edit Human	View/Edit Mouse

GDNF family receptor alpha like is a protein that in humans is encoded by the GFRAL gene. ^[5]

References