Frederick Alt

Frederick Alt
Alma mater
Scientific career
Institutions

Frederick W. Alt is an American geneticist. He is a member of the Immunology section of the National Academy of Sciences and a Charles A. Janeway Professor of Pediatrics, and Professor of Genetics at Harvard Medical School.[1] He is the Director of the Program in Cellular and Molecular Medicine at the Boston Children's Hospital. He is a Howard Hughes Medical Institute investigator since 1987.

He completed his undergraduate studies at Brandeis University, graduating in 1971, and then went on to earn a Ph.D. in Biology from Stanford University in 1977 while under the research direction of Robert Schimke. He performed his postdoctoral work in David Baltimore's laboratory at MIT. From 1982-91 he was on the faculty at Columbia University and then moved to Harvard Medical School.[2]

His research interest is in maintenance of genome stability in cells of the mammalian immunological system, particularly antigen receptor variable region gene assembly in developing B and T lymphocytes, immunoglobulin heavy chain class switch recombination (CSR), and somatic hypermutation in activated mature B lymphocytes.[1] He is the father of the chef and food writer, J. Kenji López-Alt.

Memberships and Honors

Alt is a member of:

He has received the following awards:

The Cancer Research Institute of New York gives an annual prize in his honor, the Frederick W. Alt Award for New Discoveries in Immunology.

References

  1. 1 2 Dana-Farber profile
  2. ↑ Children's Hospital bio
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