Frank Hölzle

Frank Hölzle
Born (1968-02-13) 13 February 1968
Calw
Residence Germany
Nationality German
Known for plastic facial reconstruction with a focus on micro surgery
Awards Martin-Waßmund-Prize
Scientific career
Fields Oral and maxillofacial surgery

Frank Hölzle (German pronunciation: [ˈhœltslɛ]) (born 13 February 1968 in Calw) is a German surgeon. He is a professor of oral and maxillofacial surgery at the RWTH Aachen University. He is chairman and head of the Department of Oral and Maxillofacial Surgery. Hölzle is known for his work in the fields of plastic facial reconstruction with a focus on micro surgery. He is also specialised for the treatment of tumor diseases in the head and neck region, and of malformations like cleft lip and palate.

Biography

Hölzle studied medicine and dentistry at the Free University of Berlin, at the Humboldt University of Berlin, at the University of Glasgow and at the University College London Medical School from 1989 to 1998. He received his doctoral title in human medicine in 1995. In 1998, he was promoted to doctor of dentistry. From 1999 to 2000, Hölzle was a scientific employee at the Department of Oral and Maxillofacial Surgery at the University Hospital Charité, Campus Virchow Clinic, Berlin. Hölzle worked at the Department of Oral and Maxillofacial Surgery at the Knappschaftskrankenhaus Bochum-Langendreer at the Ruhr-University Bochum from 2000 to 2007, from 2004 as deputy director. In 2002, he received recognition as a medical specialist for oral and maxillofacial surgery, and in 2005 he achieved the additional qualification as a plastic and reconstructive face surgeon. In 2006, he received venia legendi for oral and maxillofacial surgery. In 2006, he also became a Fellow of the European Board of Oral & Maxillofacial Surgeons (FEBOMFS, Barcelona). Between 1992 and 2010, Hölzle was influenced positively by Klaus-Dietrich Wolff, culminating at the Rechts der Isar Hospital of the Technical University of Munich. From 2007 to 2011, he was senior physician and deputy director of the Department of Oral and Maxillofacial Surgery at the Rechts der Isar Hospital of the Technical University of Munich. Since 2011 he has been a professor and head of the Department of Oral and Maxillofacial Surgery at the University Hospital at the RWTH Aachen University.

Scientific contribution

Hölzle studied, together with others, the following subjects: Analysis of the anatomy of microsurgical transplants and their vessel passages and histology, microcirculation, and ischemic preconditioning of microsurgical flaps, monitoring of microsurgical transplants, computer planning and surgical guides of microsurgical bone reconstruction. The research of microsurgical tissue transplants was a focus of Hölzle's scientific work. Scientific publications appeared on objectifying valuation of the viability of the transplanted tissue[1] and on the monitoring of different compound composite flaps.[2]

Furthermore, Hölzle worked on micro circulatory characteristics of these transplants and with the phenomenon of the reperfusion injury.[3] [4] After the implementation of computer planning and surgical guides technique in microsurgical bone reconstruction, Hölzle dealt with the utilisation of meaningful clinical indications and improvement of these techniques.[5][6]

Memberhips in international organisations

  • Deutsche Gesellschaft für Mund-, Kiefer- und Gesichtschirurgie,
  • Deutsche Gesellschaft für Zahn-, Mund- und Kieferheilkunde (DGZMK)
  • Workgroup of Jaw Surgery within the DGZMK.
  • Deutsche Gesellschaft für Plastische und Wiederherstellungschirurgie (DGPW)
  • Interplast-Germany
  • German Association of University Professors and Lecturers
  • Member and adviser of the Deutsch-Österreichisch-Schweizerischer Arbeitskreis für Tumoren im Kiefer- und Gesichtsbereich (DÖSAK)
  • German Councillor of the European Association for Cranio-Maxillofacial Surgery
  • Fellow of the International Team of Implantology, ITI Switzerland

Honors and awards

  • 2007 Martin-Waßmund-Prize of the Deutsche Gesellschaft für Mund-, Kiefer- und Gesichtschirurgie
  • 2008 Scientific Award Journal of Cranio-Maxillofacial Surgery für „Top 10 Cited Papers 2006–2008“, second place
  • 2009 Scientific Award Journal of Cranio-Maxillofacial Surgery, „Top 25 Hottest Articles“, third place

Publications

Books

Hölzle is coeditor of two textbooks in the field of dental surgery and of oral and maxillofacial surgery:

  • Klaus-Dietrich Wolff and Frank Hölzle (ed.): Raising of Microvascular Flaps: A Systematic Approach. Springer; 2nd ed. (2011)
  • Jochen Jackowski, Hajo Peters und Frank Hölzle (ed.): Praxisleitfaden Zahnärztliche Chirurgie. Urban & Fischer/Elsevier (2007)

Articles in scientific journals

Hölzle published more than 130 sicentific papers,[7] amongst them :

  • F. Hölzle, M. Klein, O. Schwerdtner, T. Lueth, J. Albrecht, N. Hosten, R. Felix, J. Bier: Intraoperative computed tomography with the mobile CT Tomoscan M during surgical treatment of orbital floor fractures. Int J Oral Maxillofac Surg. (2001) 30: 26–31.
  • F. Hölzle, K.-D. Wolff: Anatomic position of the lingual nerve in the mandibular third molar region with special consideration of an atrophied mandibular crest: An anatomical study. Int J Oral Maxillofac Surg. (2001) 30: 333–338.
  • F. Hölzle, D. Löffelbein, D. Nolte, K.-D. Wolff: Free flap monitoring using simultaneous non-invasive laser Doppler flowmetry and tissue spectrophotometry. J Craniomaxillofac Surg. (2006) 34: 25–33.
  • F. Hölzle, K.-D. Wolff, C. Mohr: Reconstructive oral and maxillofacial surgery. Dtsch Arztebl Int. (2008) 47: 815–22.
  • F. Hölzle, A. Rau, D. J. Loeffelbein, M. R. Kesting, T. Mücke, K.-D. Wolff: Results of monitoring fasciocutaneous, myocutaneous, osteocutaneous and perforator flaps: 4-year experience with 166 cases. Int J Oral Maxillofac Surg. (2010) 37: 21–28.
  • A. Modabber, S.C. Möhlhenrich, N. Ayoub, M. Hajji, S. Raith, S. Reich, T. Steiner, A. Ghassemi, F. Hölzle: Computer-Aided Mandibular Reconstruction with Vascularized Iliac Crest Bone Flap and Simultaneous Implant Surgery. J Oral Implantol. (2014)

References

  1. ↑ F. Hölzle, D. Löffelbein, D. Nolte, K.-D. Wolff: Free flap monitoring using simultaneous non-invasive laser Doppler flowmetry and tissue spectrophotometry. J Craniomaxillofac Surg. (2006) 34: 25–33.
  2. ↑ F. Hölzle, A. Rau, D. J. Loeffelbein, M. R. Kesting, T. Mücke, K.-D. Wolff: Results of monitoring fasciocutaneous, myocutaneous, osteocutaneous and perforator flaps: 4-year experience with 166 cases. Int J Oral Maxillofac Surg. (2010) 37: 21–28.
  3. ↑ Sönmez TT, Al-Sawaf O, Brandacher G, Kanzler I, Tuchscheerer N, Tohidnezhad M, Kanatas A, Knobe M, Fragoulis A, Tolba R, Mitchell D, Pufe T, Wruck CJ, Hölzle F, Liehn EA. A novel laser-Doppler flowmetry assisted murine model of acute hindlimb ischemia-reperfusion for free flap research. PLoS One. 2013 Jun 20;8(6):e66498. doi: 10.1371/journal.pone.0066498. Print 2013.
  4. ↑ Al-Sawaf O1, Fragoulis A, Rosen C, Keimes N, Liehn EA, Hölzle F, Kan YW, Pufe T, Sönmez TT, Wruck CJ. Nrf2 augments skeletal muscle regeneration after ischaemia-reperfusion injury. J Pathol. 2014 Dec;234(4):538-47. doi: 10.1002/path.4418. Epub 2014 Sep 16.
  5. ↑ Modabber A, Gerressen M, Ayoub N, Elvers D, Stromps JP, Riediger D, Hölzle F, Ghassemi A. Computer-assisted zygoma reconstruction with vascularized iliac crest bone graft. Int J Med Robot. 2013 Dec;9(4):497–502. doi: 10.1002/rcs.1557. Epub 2013 Nov 6.
  6. ↑ A. Modabber, S.C. Möhlhenrich, N. Ayoub, M. Hajji, S. Raith, S. Reich, T. Steiner, A. Ghassemi, F. Hölzle: Computer-Aided Mandibular Reconstruction with Vascularized Iliac Crest Bone Flap and Simultaneous Implant Surgery. J Oral Implantol. (2014)
  7. ↑ PubMed Publikationsliste (Auszug) Frank Hölzle
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