Filtration coefficient

Filtration coefficient (Kf) a measure of a membrane's permeability to water; specifically, the volume of fluid filtered in unit time through a unit area of membrane per unit pressure difference, and it defined as the glomerular filtration rate (GFR) for both kidney per millimeter of mercury (mmHg) of filtration pressure. Therefore, the glomerular filtration rate is equal to the filtration pressure multiply the filtration coefficient.^[1]^[2]^[3] The normal filtration coefficient is 12.5 ml per minute per mmHg of filtration pressure.^[3]

A high value of Kf indicates a highly water permeable capillary. A low value indicates a low capillary permeability.^[3]

The glomerular filtration coefficient depend upon:^[3]

The surface area of the filtering membrane.
The permeability of the filtering membrane.

References

↑ "Filtration coefficient - definition of filtration coefficient by Medical dictionary". TheFreeDictionary.com. Retrieved 27 December 2016.
↑ "Glomerular filtration rate". Retrieved 27 December 2016.
1 2 3 4 E. Hall, John (2011). Guyton and Hall Textbook of Medical Physiology/12th ed. United States of America. p. 181. ISBN 978-1-4160-4574-8.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[1] "Filtration coefficient - definition of filtration coefficient by Medical dictionary". TheFreeDictionary.com. Retrieved 27 December 2016.

[2] "Glomerular filtration rate". Retrieved 27 December 2016.

[book1-3] 1 2 3 4 E. Hall, John (2011). Guyton and Hall Textbook of Medical Physiology/12th ed. United States of America. p. 181. ISBN 978-1-4160-4574-8.