Fat atypical cadherin 3

FAT3
Identifiers
Aliases	FAT3, CDHF15, CDHR10, hFat3, FAT atypical cadherin 3
External IDs	MGI: 2444314 HomoloGene: 82252 GeneCards: FAT3
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	92,896,470 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	16,501,285 bp[2]
Gene ontology
Molecular function	• calcium ion binding;
Cellular component	• integral component of membrane; • plasma membrane; • membrane;
Biological process	• homophilic cell adhesion via plasma membrane adhesion molecules; • multicellular organism development; • cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	120114
	270120
	ENSG00000165323; ENSG00000282908
	ENSMUSG00000074505
	Q8TDW7
	Q8BNA6
	NM_001008781
	NM_001080814
	NP_001008781
	XP_006510436.1
	Wikidata
View/Edit Human	View/Edit Mouse

FAT atypical cadherin 3 is a protein that in humans is encoded by the FAT3 gene.^[5]

References

Berndt JD, Aoyagi A, Yang P, Anastas JN, Tang L, Moon RT (September 2011). "Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling". The Journal of Cell Biology. 194 (5): 737–50. doi:10.1083/jcb.201107021. PMC 3171123. PMID 21875946.
Zheng JS, Arnett DK, Lee YC, Shen J, Parnell LD, Smith CE, Richardson K, Li D, Borecki IB, Ordovás JM, Lai CQ (2013). "Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits". PLOS One. 8 (10): e77442. doi:10.1371/journal.pone.0077442. PMC 3810463. PMID 24204828.
Mitsui K, Nakajima D, Ohara O, Nakayama M (February 2002). "Mammalian fat3: a large protein that contains multiple cadherin and EGF-like motifs". Biochemical and Biophysical Research Communications. 290 (4): 1260–6. doi:10.1006/bbrc.2002.6338. PMID 11811999.
Wu Q (April 2005). "Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes". Genetics. 169 (4): 2179–88. doi:10.1534/genetics.104.037606. PMC 1449604. PMID 15744052.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.