Face of the Giant Panda Sign

Axial T2-weighted MRI of the brain at the level of the midbrain showing the characteristic ‘face of the giant panda’ sign, with normal red nuclei and substantia nigra (pars reticulata) against a background of hyperintensity in the tegmentum, as well as hypointensity of the superior colliculi.

The "Face of the Giant Panda" sign, "Panda Sign of the Midbrain," or "Double-Panda Sign" refers to a characteristic "panda's face" appearance in MRI images of patients suffering from Wilson's Disease. Along with Kayser–Fleischer rings, the sign is helpful in diagnosis.[1]

References

  1. ↑ Kuruvilla A, Joseph S. 'Face of the giant panda' sign in Wilson's disease : revisited. Neurol India [serial online] 2000 [cited 2015 Jun 19];48:395. Available from: http://www.neurologyindia.com/text.asp?2000/48/4/395/1490

Bibliography

  • Das SK, Ray K (September 2006). "Wilson's disease: an update". Nat Clin Pract Neurol 2 (9): 482–93. doi:10.1038/ncpneuro0291. PMID 16932613
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