FOXQ1

FOXQ1
Identifiers
Aliases	FOXQ1, HFH1, forkhead box Q1
External IDs	MGI: 1298228 HomoloGene: 7359 GeneCards: FOXQ1
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p25.3 Start 1,312,440 bp[1] End 1,314,748 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13 A3.2|13 13.46 cM Start 31,556,134 bp[2] End 31,560,976 bp[2]
Gene ontology Molecular function • transcription factor activity, sequence-specific DNA binding • sequence-specific DNA binding • DNA binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding Cellular component • cell nucleus Biological process • hair follicle morphogenesis • regulation of transcription, DNA-templated • transcription, DNA-templated • negative regulation of transcription from RNA polymerase II promoter • anatomical structure morphogenesis • cell differentiation • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	94234	15220
Ensembl	ENSG00000164379	ENSMUSG00000038415
UniProt	Q9C009	O70220
RefSeq (mRNA)	NM_033260	NM_008239
RefSeq (protein)	NP_150285	NP_032265
Location (UCSC)	Chr 6: 1.31 – 1.31 Mb	Chr 13: 31.56 – 31.56 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Forkhead box Q1 is a protein that in humans is encoded by the FOXQ1 gene. ^[5]

Function

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.