FDX1L

FDX2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Y5C
Identifiers
Aliases	FDX2, ferredoxin 1 like, FDX1L, ferredoxin 2
External IDs	MGI: 1915415 HomoloGene: 31955 GeneCards: FDX2
Gene location (Human)
Chr.	Chromosome 19 (human)[1]
End	10,316,015 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	21,073,614 bp[2]
Gene ontology
Molecular function	• iron-sulfur cluster binding; • protein binding; • metal ion binding; • 2 iron, 2 sulfur cluster binding; • electron carrier activity;
Cellular component	• mitochondrial matrix; • mitochondrion;
Biological process	• C21-steroid hormone biosynthetic process; • sterol metabolic process; • oxidation-reduction process; • small molecule metabolic process; • electron transport chain;
	Sources:Amigo / QuickGO
Orthologs
	112812
	68165
	ENSG00000267673
	ENSMUSG00000079677
	Q6P4F2
	Q9CPW2
	NM_080665; NM_001031734
	NM_001039824
	NP_001026904
	NP_001034913
	Wikidata
View/Edit Human	View/Edit Mouse

Ferredoxin 1-like is a protein that in humans is encoded by the FDX1L gene.^[5]

Mutations in FDX1L cause mitochondrial myopathy .^[6]

References

Sheftel AD, Stehling O, Pierik AJ, Elsässer HP, Mühlenhoff U, Webert H, Hobler A, Hannemann F, Bernhardt R, Lill R (June 2010). "Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis". Proceedings of the National Academy of Sciences of the United States of America. 107 (26): 11775–80. doi:10.1073/pnas.1004250107. PMC 2900682. PMID 20547883.

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