FCHSD2

FCHSD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DL5, 2DL7
Identifiers
Aliases	FCHSD2, NWK, SH3MD3, FCH and double SH3 domains 2
External IDs	MGI: 2448475 HomoloGene: 8887 GeneCards: FCHSD2
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	73,142,261 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	101,284,405 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• protein binding;
Cellular component	• neuromuscular junction; • recycling endosome;
Biological process	• neuromuscular synaptic transmission; • regulation of actin filament polymerization;
	Sources:Amigo / QuickGO
Orthologs
	9873
	207278
	ENSG00000137478
	ENSMUSG00000030691
	O94868
	Q3USJ8
	NM_014824
	NM_001146010; NM_199012
	NP_055639
	NP_001139482; NP_950177
	Wikidata
View/Edit Human	View/Edit Mouse

FCH and double SH3 domains protein 2 is a protein that in humans is encoded by the FCHSD2 gene.^[5]^[6]^[7]

Interactions

FCHSD2 has been shown to interact with MAGI1^[8] and C2orf73.^[9]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000137478 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030691 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
↑ Katoh M, Katoh M (May 2004). "Identification and characterization of human FCHSD1 and FCHSD2 genes in silico". International Journal of Molecular Medicine. 13 (5): 749–54. doi:10.3892/ijmm.13.5.749. PMID 15067381.
↑ "Entrez Gene: FCHSD2 FCH and double SH3 domains 2".
↑ Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura W, Ohnishi H, Mashima H, Fujita T, Omata M, Hata Y (November 2003). "Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains". Oncogene. 22 (52): 8422–31. doi:10.1038/sj.onc.1206996. PMID 14627983.
↑ Thalappilly S, Suliman M, Gayet O, Soubeyran P, Hermant A, Lecine P, Iovanna JL, Dusetti NJ (August 2008). "Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach". Proteomics. 8 (15): 3071–81. doi:10.1002/pmic.200701157. PMID 18654987.

Petitjean C, Scheydeker JL, Suinat JL, Rendoing J (1976). "[Pulmonary edema in hangings]". de l'Anesthésiologie Française. 16. 16 Spec No 2-3: 57–65. PMID 9873.
Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura W, Ohnishi H, Mashima H, Fujita T, Omata M, Hata Y (November 2003). "Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains". Oncogene. 22 (52): 8422–31. doi:10.1038/sj.onc.1206996. PMID 14627983.
Coyle IP, Koh YH, Lee WC, Slind J, Fergestad T, Littleton JT, Ganetzky B (February 2004). "Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila". Neuron. 41 (4): 521–34. doi:10.1016/S0896-6273(04)00016-9. PMID 14980202.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y (March 2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. doi:10.1038/nature04632. PMID 16554811.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000137478 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030691 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[pmid9872452-5] Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.

[pmid15067381-6] Katoh M, Katoh M (May 2004). "Identification and characterization of human FCHSD1 and FCHSD2 genes in silico". International Journal of Molecular Medicine. 13 (5): 749–54. doi:10.3892/ijmm.13.5.749. PMID 15067381.

[entrez-7] "Entrez Gene: FCHSD2 FCH and double SH3 domains 2".

[pmid14627983-8] Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura W, Ohnishi H, Mashima H, Fujita T, Omata M, Hata Y (November 2003). "Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains". Oncogene. 22 (52): 8422–31. doi:10.1038/sj.onc.1206996. PMID 14627983.

[9] Thalappilly S, Suliman M, Gayet O, Soubeyran P, Hermant A, Lecine P, Iovanna JL, Dusetti NJ (August 2008). "Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach". Proteomics. 8 (15): 3071–81. doi:10.1002/pmic.200701157. PMID 18654987.

FCHSD2

Interactions

References

Further reading