FAM49A

FAM49A
Identifiers
AliasesFAM49A, family with sequence similarity 49 member A
External IDsMGI: 1261783 HomoloGene: 12657 GeneCards: FAM49A
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2p24.2Start16,549,459 bp[1]
End16,666,331 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

81553

76820

Ensembl

ENSG00000197872

ENSMUSG00000020589

UniProt

Q9H0Q0

Q8BHZ0

RefSeq (mRNA)

NM_030797

NM_001146119
NM_029758
NM_001364432

RefSeq (protein)

NP_110424

NP_001139591
NP_084034
NP_001351361

Location (UCSC)Chr 2: 16.55 – 16.67 MbChr 12: 12.26 – 12.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Family with sequence similarity 49, member A, also known as FAM49A, is a protein which in humans is encoded by the FAM49A gene.[5]

Gene

Fam49A is located on human chromosome 2, at 2p24.3. It has 1512 base pairs in the reference sequence mRNA transcript.[6]

Protein

The Fam49A gene product is a 323 amino acid protein. The protein contains two domains: Residues 15-319 comprise the "Domain of Unknown Function 1394" (DUF1394, Pfam PF07159). Residues 67->281 comprise the "Cytoplasmic Fragile X Interacting Superfamily" region.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000197872 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020589 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: FAM49A family with sequence similarity 49, member A".
  6. ↑ "Nucleotide - family with sequence similarity 49, member A [Homo sapiens]". Nucleotide. National Center for Biotechnology Information, United States National Institutes of Health. Retrieved 2009-05-09.
  7. ↑ "Protein - family with sequence similarity 49, member A [Homo sapiens]". Protein. National Center for Biotechnology Information, United States National Institutes of Health. Retrieved 2009-05-09.

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.


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