Equine arteritis virus leader TRS hairpin (LTH)

Equine arteritis virus leader TRS hairpin (LTH)
Identifiers
Symbol EAV_LTH
Rfam RF00498
Other data
RNA type Cis-reg; leader
Domain(s) Viruses
SO 0000233
PDB structures PDBe

The equine arteritis virus leader transcription-regulating sequence hairpin (LTH) is as RNA element that is thought to be a key structural element in discontinuous subgenomic RNA synthesis and is critical for leader transcription-regulating sequences (TRS) function.[1] Similar structures have been predicted in other arteriviruses and coronaviruses.[2]

References

  1. Van, Den Born E; Gultyaev AP; Snijder EJ (2004). "Secondary structure and function of the 5'-proximal region of the equine arteritis virus RNA genome". RNA. 10 (3): 424&ndash, 437. doi:10.1261/rna.5174804. PMC 1370938. PMID 14970388.
  2. Liu, Y; Wimmer, E; Paul, AV (2009). "Cis-acting RNA elements in human and animal plus-strand RNA viruses". Biochimica et Biophysica Acta. 1789 (9–10): 495–517. doi:10.1016/j.bbagrm.2009.09.007. PMC 2783963. PMID 19781674.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.