Equine arteritis virus leader TRS hairpin (LTH)
Equine arteritis virus leader TRS hairpin (LTH) | |
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![]() Predicted secondary structure and sequence conservation of EAV_LTH | |
Identifiers | |
Symbol | EAV_LTH |
Rfam | RF00498 |
Other data | |
RNA type | Cis-reg; leader |
Domain(s) | Viruses |
SO | 0000233 |
PDB structures | PDBe |
The equine arteritis virus leader transcription-regulating sequence hairpin (LTH) is as RNA element that is thought to be a key structural element in discontinuous subgenomic RNA synthesis and is critical for leader transcription-regulating sequences (TRS) function.[1] Similar structures have been predicted in other arteriviruses and coronaviruses.[2]
References
- ↑ Van, Den Born E; Gultyaev AP; Snijder EJ (2004). "Secondary structure and function of the 5'-proximal region of the equine arteritis virus RNA genome". RNA. 10 (3): 424&ndash, 437. doi:10.1261/rna.5174804. PMC 1370938. PMID 14970388.
- ↑ Liu, Y; Wimmer, E; Paul, AV (2009). "Cis-acting RNA elements in human and animal plus-strand RNA viruses". Biochimica et Biophysica Acta. 1789 (9–10): 495–517. doi:10.1016/j.bbagrm.2009.09.007. PMC 2783963. PMID 19781674.
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