Enhancer of polycomb homolog 2 (drosophila)

EPC2
Identifiers
AliasesEPC2, EPC-LIKE, enhancer of polycomb homolog 2
External IDsMGI: 1278321 HomoloGene: 32274 GeneCards: EPC2
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q23.1Start148,644,440 bp[1]
End148,787,568 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26122

227867

Ensembl

ENSG00000135999

ENSMUSG00000069495

UniProt

Q52LR7

Q8C0I4

RefSeq (mRNA)

NM_015630

NM_172663

RefSeq (protein)

NP_056445

NP_766251

Location (UCSC)Chr 2: 148.64 – 148.79 MbChr 2: 49.45 – 49.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Enhancer of polycomb homolog 2 (Drosophila) is a protein that in humans is encoded by the EPC2 gene.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000135999 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000069495 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Enhancer of polycomb homolog 2 (Drosophila)".

Further reading

  • Doyon Y, Cayrou C, Ullah M, Landry AJ, Côté V, Selleck W, Lane WS, Tan S, Yang XJ, Côté J (January 2006). "ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation". Molecular Cell. 21 (1): 51–64. doi:10.1016/j.molcel.2005.12.007. PMID 16387653.
  • Kim J, Woo AJ, Chu J, Snow JW, Fujiwara Y, Kim CG, Cantor AB, Orkin SH (October 2010). "A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs". Cell. 143 (2): 313–24. doi:10.1016/j.cell.2010.09.010. PMC 3018841. PMID 20946988.
  • Kim S, Swaminathan S, Shen L, Risacher SL, Nho K, Foroud T, Shaw LM, Trojanowski JQ, Potkin SG, Huentelman MJ, Craig DW, DeChairo BM, Aisen PS, Petersen RC, Weiner MW, Saykin AJ (January 2011). "Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort". Neurology. 76 (1): 69–79. doi:10.1212/WNL.0b013e318204a397. PMC 3030225. PMID 21123754.
  • Doyon Y, Selleck W, Lane WS, Tan S, Côté J (March 2004). "Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans". Molecular and Cellular Biology. 24 (5): 1884–96. doi:10.1128/MCB.24.5.1884-1896.2004. PMC 350560. PMID 14966270.
  • Hayakawa T, Zhang F, Hayakawa N, Ohtani Y, Shinmyozu K, Nakayama J, Andreassen PR (April 2010). "MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks". Journal of Cell Science. 123 (Pt 7): 1124–30. doi:10.1242/jcs.060178. PMC 2844321. PMID 20332121.
  • Melzer D, Perry JR, Hernandez D, Corsi AM, Stevens K, Rafferty I, et al. (May 2008). "A genome-wide association study identifies protein quantitative trait loci (pQTLs)". PLoS Genetics. 4 (5): e1000072. doi:10.1371/journal.pgen.1000072. PMC 2362067. PMID 18464913.
  • Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J (June 2007). "RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation". Genes to Cells. 12 (6): 811–26. doi:10.1111/j.1365-2443.2007.01089.x. PMID 17573780.
  • Guil S, Soler M, Portela A, Carrère J, Fonalleras E, Gómez A, Villanueva A, Esteller M (June 2012). "Intronic RNAs mediate EZH2 regulation of epigenetic targets". Nature Structural & Molecular Biology. 19 (7): 664–70. doi:10.1038/nsmb.2315. PMID 22659877.
  • Huang X, Spencer GJ, Lynch JT, Ciceri F, Somerville TD, Somervaille TC (May 2014). "Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells". Leukemia. 28 (5): 1081–91. doi:10.1038/leu.2013.316. PMC 3998875. PMID 24166297.
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