ERAF

AHSP
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesAHSP, EDRF, ERAF, alpha hemoglobin stabilizing protein
External IDsHomoloGene: 9605 GeneCards: AHSP
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p11.2Start31,527,864 bp[1]
End31,528,803 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

51327

n/a

Ensembl

ENSG00000169877

n/a

UniProt

Q9NZD4

n/a

RefSeq (mRNA)

NM_016633
NM_001318221
NM_001318222

n/a

RefSeq (protein)

NP_001305150
NP_001305151
NP_057717

n/a

Location (UCSC)Chr 16: 31.53 – 31.53 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Alpha-hemoglobin-stabilizing protein is a protein that in humans is encoded by the ERAF gene.[3][4][5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000169877 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ Miele G, Manson J, Clinton M (Mar 2001). "A novel erythroid-specific marker of transmissible spongiform encephalopathies". Nat Med. 7 (3): 361–4. doi:10.1038/85515. PMID 11231637.
  4. ↑ Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachi K, Simon MC, Blobel GA, Weiss MJ (Jun 2002). "An abundant erythroid protein that stabilizes free alpha-haemoglobin". Nature. 417 (6890): 758–63. doi:10.1038/nature00803. PMID 12066189.
  5. ↑ "Entrez Gene: ERAF erythroid associated factor".

Further reading

  • Florio P, Rossi M, Sigurdardottir M, et al. (2004). "Paracrine regulation of endometrial function: interaction between progesterone and corticotropin-releasing factor (CRF) and activin A". Steroids. 68 (10–13): 801–7. doi:10.1016/S0039-128X(03)00137-5. PMID 14667971.
  • Weiss MJ, Zhou S, Feng L, et al. (2006). "Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia". Ann. N. Y. Acad. Sci. 1054: 103–17. doi:10.1196/annals.1345.013. PMID 16339656.
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  • Gell D, Kong Y, Eaton SA, et al. (2002). "Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein". J. Biol. Chem. 277 (43): 40602–9. doi:10.1074/jbc.M206084200. PMID 12192002.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Viprakasit V, Tanphaichitr VS, Chinchang W, et al. (2004). "Evaluation of alpha hemoglobin stabilizing protein (AHSP) as a genetic modifier in patients with beta thalassemia". Blood. 103 (9): 3296–9. doi:10.1182/blood-2003-11-3957. PMID 14715623.
  • Baudin-Creuza V, Vasseur-Godbillon C, Pato C, et al. (2004). "Transfer of human alpha- to beta-hemoglobin via its chaperone protein: evidence for a new state". J. Biol. Chem. 279 (35): 36530–3. doi:10.1074/jbc.M405389200. PMID 15220346.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Gallagher PG, Liem RI, Wong E, et al. (2006). "GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene". J. Biol. Chem. 280 (47): 39016–23. doi:10.1074/jbc.M506062200. PMID 16186125.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Hamdane D, Vasseur-Godbillon C, Baudin-Creuza V, et al. (2007). "Reversible hexacoordination of alpha-hemoglobin-stabilizing protein (AHSP)/alpha-hemoglobin Versus pressure. Evidence for protection of the alpha-chains by their chaperone". J. Biol. Chem. 282 (9): 6398–404. doi:10.1074/jbc.M610543200. PMID 17194704.


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