EGOT (gene)

EGOT
Identifiers
Aliases	EGOT, EGO, NCRNA00190, eosinophil granule ontogeny transcript (non-protein coding), eosinophil granule ontogeny transcript
External IDs	GeneCards: EGOT
Orthologs
	100126791
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	Wikidata
View/Edit Human

EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript (non-protein coding),^[2] is a human gene at 3p26.1 that produces a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 (ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression.^[2] Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals.^[3]

†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature.^[4]

References

↑ "Human PubMed Reference:".
1 2 Wagner LA, Christensen CJ, Dunn DM, et al. (June 2007). "EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression". Blood. 109 (12): 5191–8. doi:10.1182/blood-2006-06-027987. PMC 1890841. PMID 17351112.
↑ Rose D, Stadler PF (October 2011). "Molecular evolution of the non-coding eosinophil granule ontogeny transcript". Front Genet. 2. doi:10.3389/fgene.2011.00069. PMC 3268622. PMID 22303364.
↑ Wright, MW (Apr 9, 2014). "A short guide to long non-coding RNA gene nomenclature". Human Genomics. 8: 7. doi:10.1186/1479-7364-8-7. PMC 4021045. PMID 24716852.

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[1] "Human PubMed Reference:".

[pmid17351112-2] 1 2 Wagner LA, Christensen CJ, Dunn DM, et al. (June 2007). "EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression". Blood. 109 (12): 5191–8. doi:10.1182/blood-2006-06-027987. PMC 1890841. PMID 17351112.

[pmid22303364-3] Rose D, Stadler PF (October 2011). "Molecular evolution of the non-coding eosinophil granule ontogeny transcript". Front Genet. 2. doi:10.3389/fgene.2011.00069. PMC 3268622. PMID 22303364.

[4] Wright, MW (Apr 9, 2014). "A short guide to long non-coding RNA gene nomenclature". Human Genomics. 8: 7. doi:10.1186/1479-7364-8-7. PMC 4021045. PMID 24716852.