Doramectin

Doramectin
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration		 Injection, Topical and Oral
ATCvet code
Legal status
Legal status
  • Veterinary use only
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ECHA InfoCard 100.123.125 Edit this at Wikidata
Chemical and physical data
Formula C50H74O14
Molar mass 899.114
  (verify)

Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.[1]

It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Its spectrum includes: Haemonchus, Ostertagia, Trichostrongylus, Cooperia, and Oesophagostomum species and Dictyocaulus viviparus, Dermatobia hominis, Boophilus microplus, and Psoroptes bovis, among many other internal and external parasites. It is available as an injection and as a 5-mg/ml topical solution.

Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufactured by Agrovet Market Animal Health[2]) in a 1% Doramectin Long Acting Injectable Solution for cattle, sheep, swine[3] and others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation, extending its action up to 42 days.

Doramectin is also available for horses[3] as an oral, flavored, bioadhesive gel under the name Doraquest L.A. Oral Gel.[4] It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.

References

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