DnaX ribosomal frameshifting element

DnaX ribosomal frameshifting element
Identifiers
Symbol DnaX
Rfam RF00382
Other data
RNA type Cis-reg; frameshift_element
Domain(s) Bacteria
SO 0005836
PDB structures PDBe

The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two encoded products, tau and gamma, which are produced in a 1:1 ratio. The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are DNA polymerase III subunits.[1][2]

References

  1. Larsen, B; Gesteland RF; Atkins JF (1997). "Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50%". J Mol Biol. 271 (1): 47&ndash, 60. doi:10.1006/jmbi.1997.1162. PMID 9300054.
  2. Blinkova, A; Burkart MF; Owens TD; Walker JR (1997). "Conservation of the Escherichia coli dnaX programmed ribosomal frameshift signal in Salmonella typhimurium". J Bacteriol. 179 (13): 4438&ndash, 4442. PMC 179275. PMID 9209069.
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