DNAJC1

DNAJC1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDNAJC1, DNAJL1, ERdj1, HTJ1, MTJ1, DnaJ heat shock protein family (Hsp40) member C1
External IDsMGI: 103268 HomoloGene: 7293 GeneCards: DNAJC1
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10p12.31Start21,756,537 bp[1]
End22,003,769 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

64215

13418

Ensembl

ENSG00000136770

ENSMUSG00000026740

UniProt

Q96KC8

Q61712

RefSeq (mRNA)

NM_022365

NM_001190817
NM_007869

RefSeq (protein)

NP_071760

NP_001177746
NP_031895

Location (UCSC)Chr 10: 21.76 – 22 MbChr 2: 18.2 – 18.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DnaJ homolog subfamily C member 1 is a protein that in humans is encoded by the DNAJC1 gene.[5]

Interactions

DNAJC1 has been shown to interact with Alpha 1-antichymotrypsin.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000136770 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026740 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1".
  6. ↑ Kroczynska B, Evangelista CM, Samant SS, Elguindi EC, Blond SY (2004). "The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity". J. Biol. Chem. 279 (12): 11432–43. doi:10.1074/jbc.M310903200. PMC 1553221. PMID 14668352.

Further reading

  • Kroczynska B, King-Simmons L, Alloza L, et al. (2006). "BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4". Biochem. Biophys. Res. Commun. 338 (3): 1467–77. doi:10.1016/j.bbrc.2005.10.101. PMID 16271702.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Kroczynska B, Evangelista CM, Samant SS, et al. (2004). "The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity". J. Biol. Chem. 279 (12): 11432–43. doi:10.1074/jbc.M310903200. PMC 1553221. PMID 14668352.
  • Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Chevalier M, Rhee H, Elguindi EC, Blond SY (2000). "Interaction of murine BiP/GRP78 with the DnaJ homologue MTJ1". J. Biol. Chem. 275 (26): 19620–7. doi:10.1074/jbc.M001333200. PMC 1534116. PMID 10777498.


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