Christa Brosseau

Christa L. Brosseau is a Canadian chemist, currently a Canada Research Chair at Saint Mary's University (Halifax). Brosseau's research aims to understand the unique optical and electronic properties observed when certain nanoscale metals interact with light, using sustainable plasmonic materials to develop state-of-the-art molecular sensors.[1]

Early career and education

Brosseau was born in Halifax, Nova Scotia, and received a B.Sc. degree in chemistry from Dalhousie University and a MSc degree in 2003 under the supervision of Prof. Sharon Roscoe at Acadia University for studying the adsorption of proteins on metallic surfaces using electrochemical methods.

Graduate Studies

In 2007, Brosseau completed a PhD at the University of Guelph under the supervision of Prof. Jacek Lipkowski on a project which involved using electrochemistry and infrared spectroscopy to probe the interaction of cholera toxin with a model biological membrane supported on an electrode surface.

Postdoctoral Studies

In 2007, Brosseau received an Andrew W. Mellon Foundation postdoctoral fellowship to work at Northwestern University under the supervision of Prof. Richard P. Van Duyne, in collaboration with the Art Institute of Chicago. This project used surface-enhanced Raman spectroscopy (SERS) to analyze colorants in historical textiles and paintings.

Research

In 2009, Brosseau joined the Chemistry department at Saint Mary's University as an Assistant Professor, and was promoted to Associate Professor in 2014. Brosseau was named the Canada Research Chair in Sustainable Chemistry and Materials in 2016.[2][1]

The Brosseau research lab aims to understand the unique optical and electronic properties observed when certain nanoscale metals interact with light, using sustainable plasmonic materials to develop state-of-the-art molecular sensors.[3] They were the first to synthesize silver particles (AgNPs) using avocado pit extract (APE), establishing the improved SERS performance of these APE AgNPs over traditionally synthesized AgNPs,[4] and the first to use Electrochemical surface-enhanced Raman spectroscopy (EC-SERS) to investigate protein aggregate – biomembrane interaction.[5] The Brosseau Lab also coupled SERS for the first time to a rapid vertical flow (RVF) immunotechnology for detection of anti-HCV antibodies, which shows enormous potential for next-generation Point-of-care (POC) diagnostics.[6]

Brosseau's early achievements include quantitative detection of uric acid for rapid and routine diagnosis of early preeclampsia using EC-SERS,[7] and developing a simple, portable EC-SERS spectroscopy system, consisting of a small benchtop Raman spectrometer, a laptop computer, and a portable USB potentiostat.[8] Brosseau was also involved in the first extractionless, nonhydrolysis direct SERS study of multiple artist materials, including identification of natural and synthetic colorants and organic pigments contained in historic artists' pastels spanning a broad range of chemical classes: polyphenols, rhodamines, azo pigments, and anthraquinones.[9]

Awards and Honors

Brosseau was named the Canada Research Chair in Sustainable Chemistry and Materials in 2016.

Electrochemical Society (ECS) –Vice-Chairperson of Canadian section

References

  1. 1 2 "The Brossard Group". smu.ca/academics/departments/chemistry-faculty-and-staff-christa.html.
  2. ↑ "Brosseau Lab".
  3. ↑ Brosseau, Christa (2018). "Research Gate".
  4. ↑ Brossard, Christa; Lynk, T.P.; Clarke, O.J.R.; Kesavan, N. (2018). "Development of a Sustainable Plasmon-Enhanced Spectroelectric Hemical Sensor using Avocado Pit (Persea Americana) Extract". Sensors and Actuators B: Chemical. 257: 270–277.
  5. ↑ Brosseau, Christa; Karaballi, R.A.; Merchant, S.; Power, S.R. (2018). "Electrochemical Surface-Enhanced Raman Spectroscopy (EC-SERS) Study of the Interaction between Protein Aggregates and Biomimetic Membranes". Physical Chemistry Chemical Physics. 20: 4513–4526.
  6. ↑ Brosseau, Christa; Clarke, O.J.R.; Goodall, B.L.; Hui, H.P.; Vats, N. (2018). "Development of a SERS-Based Rapid Vertical Flow Assay for Point-Of-Care Diagnostics". Analytical Chemistry. 89 (3): 1405.
  7. ↑ Brosseau, Christa; Zhao, L.; Blackburn, J. (2015). "Quantitative Detection of Uric Acid by Electrochemical Surface Enhanced Raman Spectroscopy (EC-SERS) Using a Multilayered Au/Ag Substrate". Analytical Chemistry. 87 (1): 441.
  8. ↑ Brosseau, Christa; Robinson, A.; Harroun, S.; Bergman, J. (2012). "A Portable Electrochemical SERS system for Routine Spectroelectrochemical Analysis". Analytical Chemistry. 84: 1760.
  9. ↑ Brosseau, Christa; Rayner, K.; Casadio, F.; Grzywacz, C.M.; Van Duyne, R.P. (2009). "Surface-Enhanced Raman Spectroscopy: A Direct Method to Identify Colorants in Various Artist Media". Analytical Chemistry. 81 (17): 7443.


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