Chloroacetamide

Chloroacetamide
Names
IUPAC name
2-Chloroacetamide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.001.068
EC Number 201-174-2
Properties
C2H4ClNO
Molar mass 93.51 g·mol−1
Appearance Colorless or yellow crystals
Melting point 120 °C (248 °F; 393 K)
90 g/L at 25°C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Chloroacetamide (2-chloroacetamide) is a chlorinated organic compound with the molecular formula CHCl2CONH2. It is used as an herbicide[1] and a preservative.[2] It is a colorless (older samples appear yellow) crystalline substance with characteristic smell, readily soluble in water.[3]

Production

It is produced by ammonolysis of the methyl ester:[4]

ClCH2CO2CH3 + NH3 → ClCH2C(O)NH2 + CH3OH

Hazards

Chloroacetamide is toxic, irritates eyes and skin, and may cause an allergic reaction. It is suspected of reproductive toxicity and teratogenicity.[5] It decomposes when heated above 225 °C and creates toxic gases including chlorine and nitrogen oxides.[3]

See also

References

  1. Herbicides - Epochem Archived 2008-05-20 at the Wayback Machine.
  2. Acetamide, 2-chloro- - Government of Canada Archived 2009-01-31 at the Wayback Machine.
  3. 1 2 2-CHLOROACETAMIDE
  4. Koenig, G.; Lohmar, E.; Rupprich, N., "Chloroacetic Acids", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, doi:10.1002/14356007.a06_537
  5. "DECISION du 14 juin 2012" (PDF) (in French). Agence Nationale de Sécurité du Médicament et des Produits de Santé.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.