Chemoprotective agent

In the treatment of cancer, chemoprotective agents are drugs which protect healthy tissue from the toxic effects of anticancer drugs.

Examples[1][2] include:

  • Amifostine, approved by the FDA in 1995, which helps prevent kidney damage in patients undergoing cisplatin and carboplatin chemotherapy
  • Mesna, approved by the FDA in 1988, which helps prevent hemorrhagic cystitis (bladder bleeding) in patients undergoing cyclophosphamide or ifosfamide chemotherapy
  • Dexrazoxane, approved by the FDA in 1995, which helps prevent heart problems in patients undergoing doxorubicin chemotherapy

References

  1. ↑ Cancer, Cleveland Clinic. "Chemoprotective Agents: Amifostine, Mesna, Dexrazoxane - What is Chemotherapy? - Chemocare". chemocare.com. Retrieved 2016-10-13.
  2. ↑ First Aid for the USMLE Step 1 2016. ISBN 9781259587375.

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.