Cerebral dopamine neurotrophic factor

CDNF
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCDNF, ARMETL1, cerebral dopamine neurotrophic factor
External IDsMGI: 3606576 HomoloGene: 27965 GeneCards: CDNF
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10p13Start14,819,250 bp[1]
End14,838,575 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

441549

227526

Ensembl

ENSG00000185267

ENSMUSG00000039496

UniProt

Q49AH0

Q8CC36

RefSeq (mRNA)

NM_001029954

NM_177647

RefSeq (protein)

NP_001025125

NP_808315

Location (UCSC)Chr 10: 14.82 – 14.84 MbChr 2: 3.51 – 3.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cerebral dopamine neurotrophic factor also known as ARMET-like protein 1 or is a protein that in humans that is encoded by the CDNF gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000185267 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039496 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Cerebral dopamine neurotrophic factor".
  6. ↑ Lindholm P, Voutilainen MH, Laurén J, Peränen J, Leppänen VM, Andressoo JO, Lindahl M, Janhunen S, Kalkkinen N, Timmusk T, Tuominen RK, Saarma M (Jul 2007). "Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo". Nature. 448 (7149): 73–7. doi:10.1038/nature05957. PMID 17611540.

Further reading

  • Choi JM, Hong JH, Chae MJ, Ngyuen PH, Kang HS, Ma HI, Kim YJ (Apr 2011). "Analysis of mutations and the association between polymorphisms in the cerebral dopamine neurotrophic factor (CDNF) gene and Parkinson disease". Neuroscience Letters. 493 (3): 97–101. doi:10.1016/j.neulet.2011.02.013. PMID 21320571.
  • Xu XR, Huang J, Xu ZG, Qian BZ, Zhu ZD, Yan Q, Cai T, Zhang X, Xiao HS, Qu J, Liu F, Huang QH, Cheng ZH, Li NG, Du JJ, Hu W, Shen KT, Lu G, Fu G, Zhong M, Xu SH, Gu WY, Huang W, Zhao XT, Hu GX, Gu JR, Chen Z, Han ZG (Dec 2001). "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver". Proceedings of the National Academy of Sciences of the United States of America. 98 (26): 15089–94. doi:10.1073/pnas.241522398. PMC 64988. PMID 11752456.
  • Lohoff FW, Bloch PJ, Ferraro TN, Berrettini WH, Pettinati HM, Dackis CA, O'Brien CP, Kampman KM, Oslin DW (Apr 2009). "Association analysis between polymorphisms in the conserved dopamine neurotrophic factor (CDNF) gene and cocaine dependence". Neuroscience Letters. 453 (3): 199–203. doi:10.1016/j.neulet.2009.02.026. PMC 2680755. PMID 19429035.
  • Parkash V, Lindholm P, Peränen J, Kalkkinen N, Oksanen E, Saarma M, Leppänen VM, Goldman A (Apr 2009). "The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional". Protein Engineering, Design & Selection. 22 (4): 233–41. doi:10.1093/protein/gzn080. PMID 19258449.
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