CXXC5

CXXC5
Identifiers
Aliases	CXXC5, CF5, RINF, WID, HSPC195, CXXC finger protein 5
External IDs	MGI: 1914643 HomoloGene: 9517 GeneCards: CXXC5
Gene location (Human)
Chr.	Chromosome 5 (human)[1]
End	139,683,882 bp[1]
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)[2]
End	35,861,687 bp[2]
Gene ontology
Molecular function	• sequence-specific DNA binding; • DNA binding; • zinc ion binding; • transcription factor binding; • protein binding; • signal transducer activity; • metal ion binding;
Cellular component	• cell nucleus; • nucleoplasm; • cytoplasm; • cytosol;
Biological process	• positive regulation of I-kappaB kinase/NF-kappaB signaling; • negative regulation of transcription from RNA polymerase II promoter; • transcription, DNA-templated; • signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	51523
	67393
	ENSG00000171604
	ENSMUSG00000046668
	Q7LFL8
	Q91WA4
NM_016463; NM_001317199; NM_001317200; NM_001317201; NM_001317202;
	NM_001317203; NM_001317204; NM_001317205; NM_001317206; NM_001317207; NM_001317208; NM_001317209; NM_001317210; NM_001317211
	NM_133687; NM_001357458; NM_001357459
NP_001304128; NP_001304129; NP_001304130; NP_001304131; NP_001304132;
	NP_001304133; NP_001304134; NP_001304135; NP_001304136; NP_001304137; NP_001304138; NP_001304139; NP_001304140; NP_057547
	NP_598448; NP_001344387; NP_001344388
	Wikidata
View/Edit Human	View/Edit Mouse

CXXC-type zinc finger protein 5 is a protein that in humans is encoded by the CXXC5 gene.^[5]^[6]^[7]^[8]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000171604 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046668 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
↑ Andersson T, Sodersten E, Duckworth JK, Cascante A, Fritz N, Sacchetti P, Cervenka I, Bryja V, Hermanson O (Feb 2009). "CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells". J Biol Chem. 284 (6): 3672–81. doi:10.1074/jbc.M808119200. PMID 19001364.
↑ Pendino F, Nguyen E, Jonassen I, Dysvik B, Azouz A, Lanotte M, Segal-Bendirdjian E, Lillehaug JR (Apr 2009). "Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis". Blood. 113 (14): 3172–81. doi:10.1182/blood-2008-07-170035. PMID 19182210.
↑ "Entrez Gene: CXXC5 CXXC finger 5".

Human CXXC5 genome location and CXXC5 gene details page in the UCSC Genome Browser.

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

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