CTNNAL1

CTNNAL1
Identifiers
AliasesCTNNAL1, ACRP, CLLP, alpha-CATU, catenin alpha like 1
External IDsMGI: 1859649 HomoloGene: 2815 GeneCards: CTNNAL1
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q31.3Start108,942,569 bp[1]
End109,013,529 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8727

54366

Ensembl

ENSG00000119326

ENSMUSG00000038816

UniProt

Q9UBT7

O88327

RefSeq (mRNA)

NM_001286974
NM_003798

NM_018761

RefSeq (protein)

NP_001273903
NP_003789

NP_061231

Location (UCSC)Chr 9: 108.94 – 109.01 MbChr 4: 56.81 – 56.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha-catulin is a protein that in humans is encoded by the CTNNAL1 gene.[5][6]

Interactions

CTNNAL1 has been shown to interact with AKAP13.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000119326 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038816 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI (Jan 1999). "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin". Genomics. 54 (1): 149–54. doi:10.1006/geno.1998.5458. PMID 9806841.
  6. ↑ "Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1".
  7. ↑ Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (Nov 2002). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200. PMID 12270917.

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Janssens B, Staes K, van Roy F (1999). "Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing". Biochim. Biophys. Acta. 1447 (2–3): 341–7. doi:10.1016/s0167-4781(99)00170-0. PMID 10542337.
  • Demacio PC, Ray PN (2002). "Alpha-catulin maps to the familial dysautonomia region on 9q31". Genome. 44 (6): 990–4. doi:10.1139/gen-44-6-990. PMID 11768226.
  • Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (2003). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200. PMID 12270917.
  • Shieh YS, Chang LC, Chiu KC, Wu CW, Lee HS (2003). "Cadherin and catenin expression in mucoepidermoid carcinoma: correlation with histopathologic grade, clinical stage, and patient outcome". J. Oral Pathol. Med. 32 (5): 297–304. doi:10.1034/j.1600-0714.2003.00144.x. PMID 12694354.
  • Surpili MJ, Delben TM, Kobarg J (2004). "Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1". Biochemistry. 42 (51): 15369–76. doi:10.1021/bi034575v. PMID 14690447.
  • Merdek KD, Nguyen NT, Toksoz D (2004). "Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling". Mol. Cell. Biol. 24 (6): 2410–22. doi:10.1128/mcb.24.6.2410-2422.2004. PMC 355851. PMID 14993280.


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