CNOT3

CNOT3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCNOT3, LENG2, NOT3, NOT3H, CCR4-NOT transcription complex subunit 3
External IDsMGI: 2385261 HomoloGene: 133900 GeneCards: CNOT3
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.42Start54,137,717 bp[1]
End54,155,708 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4849

232791

Ensembl

ENSMUSG00000035632

UniProt

O75175

Q8K0V4

RefSeq (mRNA)

NM_014516

NM_146176

RefSeq (protein)

NP_055331

NP_666288

Location (UCSC)Chr 19: 54.14 – 54.16 MbChr 7: 3.65 – 3.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CCR4-NOT transcription complex subunit 3 is a protein that in humans is encoded by the CNOT3 gene.[5][6][7]

Interactions

CNOT3 has been shown to interact with CNOT8.[5]

References

  1. 1 2 3 ENSG00000277600, ENSG00000276082, ENSG00000277114, ENSG00000274176, ENSG00000277615, ENSG00000273943, ENSG00000274941, ENSG00000275979, ENSG00000274616 GRCh38: Ensembl release 89: ENSG00000088038, ENSG00000277600, ENSG00000276082, ENSG00000277114, ENSG00000274176, ENSG00000277615, ENSG00000273943, ENSG00000274941, ENSG00000275979, ENSG00000274616 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035632 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT (Mar 2000). "Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits". Nucleic Acids Res. 28 (3): 809–17. doi:10.1093/nar/28.3.809. PMC 102560. PMID 10637334.
  6. ↑ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  7. ↑ "Entrez Gene: CNOT3 CCR4-NOT transcription complex, subunit 3".

Further reading

  • Wende H, Volz A, Ziegler A (2000). "Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster". Immunogenetics. 51 (8–9): 703–13. doi:10.1007/s002510000187. PMID 10941842.
  • Aoki T, Okada N, Wakamatsu T, Tamura TA (2002). "TBP-interacting protein 120B, which is induced in relation to myogenesis, binds to NOT3". Biochem. Biophys. Res. Commun. 296 (5): 1097–103. doi:10.1016/S0006-291X(02)02031-4. PMID 12207886.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Yin X, Warner DR, Roberts EA, Pisano MM, Greene RM (2005). "Identification of novel CBP interacting proteins in embryonic orofacial tissue". Biochem. Biophys. Res. Commun. 329 (3): 1010–7. doi:10.1016/j.bbrc.2005.02.075. PMID 15752756.
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