CMTM2

CMTM2
Identifiers
AliasesCMTM2, CKLFSF2, CKLF like MARVEL transmembrane domain containing 2
External IDsMGI: 2447311 HomoloGene: 88915 GeneCards: CMTM2
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16q21Start66,579,448 bp[1]
End66,588,275 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

146225

75502

Ensembl

ENSG00000140932

ENSMUSG00000035785

UniProt

Q8TAZ6

Q9DAC0

RefSeq (mRNA)

NM_144673
NM_001199317

NM_028524

RefSeq (protein)

NP_001186246
NP_653274

NP_082800

Location (UCSC)Chr 16: 66.58 – 66.59 MbChr 8: 104.32 – 104.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CKLF-like MARVEL transmembrane domain-containing protein 2 is a protein that in humans is encoded by the CMTM2 gene.[5]

This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000140932 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035785 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: CMTM2 CKLF-like MARVEL transmembrane domain containing 2".

Further reading

  • Liu G, Xin ZC, Chen L, et al. (2007). "Expression and localization of CKLFSF2 in human spermatogenesis". Asian J. Androl. 9 (2): 189–198. doi:10.1111/j.1745-7262.2007.00249.x. PMID 17334588.
  • Shi S, Rui M, Han W, et al. (2005). "CKLFSF2 is highly expressed in testis and can be secreted into the seminiferous tubules". Int. J. Biochem. Cell Biol. 37 (8): 1633–1640. doi:10.1016/j.biocel.2004.04.028. PMID 15896670.
  • Xu M, Yang S, Gao Y, et al. (2005). "A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene". Int. J. Biochem. Cell Biol. 37 (6): 1296–1307. doi:10.1016/j.biocel.2005.01.004. PMID 15778092.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
  • Han W, Ding P, Xu M, et al. (2004). "Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation". Genomics. 81 (6): 609–617. doi:10.1016/S0888-7543(03)00095-8. PMID 12782130.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Denef B, Werf FV, Geest HD, Kesteloot H (1976). "Calibrated apexcardiography and assessment of left ventricular dynamics in man". European journal of cardiology. 4 Suppl: 143–52. PMID 1278213.


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